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Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle
Since the discovery of γ-tubulin, attention has focused on its involvement as a microtubule nucleator at the centrosome. However, mislocalization of γ-tubulin away from the centrosome does notExpand
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Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows
Asymmetric cell divisions are essential for the development of multicellular organisms. To proceed, they require an initially symmetric cell to polarize. In Caenorhabditis elegans zygotes,Expand
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Muscle Cells Provide Instructions for Planarian Regeneration
Regeneration requires both potential and instructions for tissue replacement. In planarians, pluripotent stem cells have the potential to produce all new tissue. The identities of the cells thatExpand
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PAR-4/LKB1 Mobilizes Nonmuscle Myosin through Anillin to Regulate C. elegans Embryonic Polarization and Cytokinesis
BACKGROUND The serine/threonine kinase LKB1 regulates cell growth and polarity in metazoans, and loss of LKB1 function is implicated in the development of some epithelial cancers. Despite itsExpand
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Biophysics of Cell Developmental Processes: A Lasercutter's Perspective
Mechanics play an important role in many processes in cell and developmental biology. Forces and tension are generated within single cells and ensembles of cells within living organisms, and theyExpand
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