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A new generation of sub-second multi-slices computed tomography (MSCT) scanners, which allow a complete coronary coverage, is becoming widely available. Nevertheless, they need to be associated with 3D processing tools to quantify the coronary diseases. This study proposes to evaluate a new 3D moment-based method for the extraction of the coronary network(More)
A statistical methodology is proposed to rank several estimation methods of a relevant clinical parameter when no gold standard is available. Based on a regression without truth method, the proposed approach was applied to rank eight methods without using any a priori information regarding the reliability of each method and its degree of automation. It was(More)
The main objective of this work is to track the aortic valve plane in intra-operative fluoroscopic images in order to optimize and secure Transcatheter Aortic Valve Implantation (TAVI) procedure. This paper is focused on the issue of aortic valve calcifications tracking in fluoroscopic images. We propose a new method based on the Tracking-Learning-Detection(More)
This work aimed at combining different segmentation approaches to produce a robust and accurate segmentation result. Three to five segmentation results of the left ventricle were combined using the STAPLE algorithm and the reliability of the resulting segmentation was evaluated in comparison with the result of each individual segmentation method. This(More)
Cardiac Resynchronization Therapy (CRT) can be optimized by the fusion of anatomical, functional and electrical information in a unified framework in order to identify the most effective pacing sites. The aim of this work is to perform a registration between dynamic CT and ultrasound (US) images (2D speckle tracking mode). The proposed registration approach(More)
BACKGROUND Meta-analyses have confirmed the high performance of multislice computed tomography (MSCT) in coronary stenosis detection. Recent reports have described the study of left ventricular anatomy and function and coronary venous anatomy with MSCT. AIMS We sought to compare, in patients with cardiomyopathy of unknown origin, the performance of MSCT(More)
The selective 5HT uptake inhibitor, litoxetine (SL 81.0385), currently under development as an antidepressant was shown to have antiemetic properties in the ferret. Litoxetine (at 1 and 10 mg/kg i.v.) dose dependently reduced the number of retches and vomiting as well as the number of emetic episodes induced by cisplatin (10 mg/kg i.v.) and delayed the(More)
This manuscript describes our recent developments towards better understanding of the mechanisms amenable to cardiac resynchronization therapy response. We report the results from a full multimodal dataset corresponding to eight patients from the euHeart project. The datasets include echocardiography, MRI and electrophysiological studies. We investigate two(More)
Cardiac resynchronization therapy (CRT) has been shown to improve cardiovascular function in specific patients suffering from heart failure. This procedure still needs to be optimized to overcome the high rate of implanted patients that do not respond to this therapy. We propose in this work a better characterization of the electro-mechanical (EM) coupling(More)
Bone microarchitecture is an important determinant of the fracture risk, independently of bone mineral density. At present, bone biopsy is required for microarchitecture assessment, and accessible non-invasive techniques are needed. In this study, we tested the short-term reproducibility and parameter changes of a non-invasive method for microarchitecture(More)