Miranda M.L. van Rijen

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The objective of this study was to determine the costs and benefits of the MRSA Search and Destroy policy in a Dutch hospital during 2001 through 2006. Variable costs included costs for isolation, contact tracing, treatment of carriers and closure of wards. Fixed costs were the costs for the building of isolation rooms and the salary of one full-time(More)
Nasal carriage is an important risk factor for the development of post-operative infections with Staphylococcus aureus and pre-operative treatment with mupirocin in carriers reduces the post-operative infection rate. Therefore, it is important to identify nasal carriage rapidly. Two polymerase chain reaction (PCR) techniques were compared to conventional(More)
1Laboratory for Microbiology and Infection Control, Amphia Hospital, Breda, The Netherlands, 2Amphia Academy Infectious Disease Foundation, Amphia Hospital, Breda, The Netherlands, 3 Laboratory for Medical Microbiology and Immunology, St. Elisabeth Hospital, Tilburg, The Netherlands, 4Section Infectious Disease Control, Regional Health Authority, Leiden,(More)
OBJECTIVES: We previously demonstrated that diaspirin crosslinked hemoglobin (DCLHb, Baxter Healthcare Corp.) improves systemic oxygen uptake in sepsis. Therefore, our objective was to study the effects of DCLHb on microcirculatory blood flow in septic rats. DESIGN: Prospective and randomized experimental study in a university-affiliated laboratory.(More)
1Laboratory for Microbiology and Infection Control, Amphia Hospital, Breda, The Netherlands 2Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands 3Department of Medical Microbiology and Infection Control, VU Medical Centre, Amsterdam, The Netherlands 4Department of Medical Microbiology,(More)
OBJECTIVES: Inflammatory mediators appear to play key role in the development of adult respiratory distress syndrome (ARDS) in critically ill patients. Cytokines involved in the early phase include tumor necrosis factor alpha (TNFa) and selected interleukins. Experimental infusion of TNFa has been shown to cause ARDS and increased concentration of cytokines(More)
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