A physical map of a genome is an essential guide for navigation, allowing the location of any gene or other landmark in the chromosomal DNA. We have constructed a physical map of the mouse genome that contains 296 contigs of overlapping bacterial clones and 16,992 unique markers. The mouse contigs were aligned to the human genome sequence on the basis of… (More)
As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC library. These BAC clones provide approximately 13-fold redundant coverage of the genome and have been assembled into 376 fingerprint contigs. A yeast artificial… (More)
Publications found online in 2002. A microarray-based, integrated approach to identify novel regulators of cancer drug response and apoptosis. efficient strategy for large-scale high-throughput transposon-mediated sequencing of cDNA clones. Interaction between two E3 ubiquitin ligases of different classes, CBLC and AIP4/ITCH.