Minoru Maruyama

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Diabetes, a disease in which carbohydrate and lipid metabolism are regulated improperly by insulin, is a serious worldwide health issue. Insulin is secreted from pancreatic beta cells in response to elevated plasma glucose, with various factors modifying its secretion. Free fatty acids (FFAs) provide an important energy source as nutrients, and they also(More)
We searched for peptidic ligands for orphan G protein-coupled receptors utilizing a human genome data base and identified a new gene encoding a preproprotein that could generate a peptide. This peptide consisted of 43 amino acid residues starting from N-terminal pyroglutamic acid and ending at C-terminal arginine-phenylalanine-amide. We therefore named it(More)
We isolated a cDNA encoding an orphan G protein-coupled receptor, TGR7, which has been recently reported to correspond to MrgD. To search for ligands for TGR7, we screened a series of small molecule compounds by detecting the Ca2+ influx in Chinese hamster ovary cells expressing TGR7. Through this screening, we found that beta-alanine at micromolar doses(More)
The objective of this study is to produce a system that would allow music symbols to be written by hand using a pen-based computer that would simulate the feeling of writing on sheets of paper and that would also accurately recognize the music symbols. To accomplish these objectives, the following methods are proposed: (1) Two features, time-series data and(More)
The hidden Markov model (HMM) has been successfully applied to various kinds of on-line recognition problems including, speech recognition, handwritten character recognition, etc. In this paper, we propose an on-line method to recognize handwritten music scores. To speed up the recognition process and improve usability of the system, the following methods(More)
Both multilayer perceptrons (MLP) and Generalized Radial Basis Functions GRBF) have good approximation properties, theoretically and experimentally. Are they related? The main point of this paper 'is to show that for normalized inputs, multilayer perceptron networks are radial function networks albeit wth a non-standard radial function). This provides an(More)
In this correspondence, we describe a range sensing method by projecting a single pattern of multiple slits. To obtain 3-D data by projecting multiple slits at a time, each slit must be identified. In our method, random dots are used to identify each slit. The random dots are given as randomly distributed cuts on each slit. Thus, each slit is divided into(More)
This paper presents a digits classification system to recognize telephone numbers written on signboards. Candidate regions of digits are extracted from an image through edge extraction, enhancement and labeling. Since the digits in the images often have skew and slant, the digits are recognized after the skew and slant correction. To correct the skew, Hough(More)
The objective of this study is to produce a system that would allow music symbols to be written by hand using a pen-based computer that would simulate the feeling of writing on sheets of paper and that would also accurately recognize the music symbols. To accomplish these objectives, the following methods are proposed: (1) Two features, time-series data and(More)