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  • Rigoux L, Sigaud O, Terekhov A, Guigon E, R Shadmehr, J J O De Xivry +2 others
  • 2010
The central nervous system elaborates well-coordinated movements in spite of unexpected and unpredictable events that interfere with their goal (e.g. intrinsic noise, external forces, target displacements,. . .). Comparisons between unperturbed and perturbed motor acts reveal that the movement duration is dynamically adjusted in response to perturbations(More)
Let us assume that the purpose of any movement is to position our body in a more advantageous or rewarding state. For example, we might make a saccade to foveate an image because our brain assigns an intrinsic value to the information that it expects to acquire at the endpoint of that saccade. Different images might have different intrinsic values. Optimal(More)
Why do movements take a characteristic amount of time, and why do diseases that affect the reward system alter control of movements? Suppose that the purpose of any movement is to position our body in a more rewarding state. People and other animals discount future reward as a hyperbolic function of time. Here, we show that across populations of people and(More)
The cerebellum may monitor motor commands and through internal feedback correct for anticipated errors. Saccades provide a test of this idea because these movements are completed too quickly for sensory feedback to be useful. Earlier, we reported that motor commands that accelerate the eyes toward a constant amplitude target showed variability. Here, we(More)
When we applied a single pulse of transcranial magnetic stimulation (TMS) to any part of the human head during a saccadic eye movement, the ongoing eye velocity was reduced as early as 45 ms after the TMS, and lasted ∼32 ms. The perturbation to the saccade trajectory was not due to a mechanical effect of the lid on the eye (e.g., from blinks). When the(More)
BACKGROUND/AIMS Visually guided saccades and gaze-fixation ability were recorded in patients with early Parkinson's disease (PD). METHODS Magnetic search coil system was used to measure horizontal and vertical eye positions. RESULTS 'Staircase' visually guided saccades (multiple hypometric saccades separated by an intersaccadic interval) and 'staircase'(More)
Despite advances in adult electrocardiography (ECG) and signal processing techniques, the analysis of fetal ECGs (fECG) is still in its infancy. The clinical potential of abdominal fECG monitoring by placing electrodes over mother's abdomen in antepartum (prior to labor) has been hampered by difficulties in obtaining a reliable fECG. We propose an algorithm(More)
Many real-world datasets suffer from missing or incomplete data. In the healthcare setting, for example, certain patient measurement parameters, such as vitals and/or lab values, may be missing due to insufficient monitoring. When present, however, these features could be highly discriminative in predicting aspects of patient state. Therefore, it is(More)
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