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The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.

• Jessica A. Hamerman, Minjian Ni, Justin R. Killebrew, Ching-Liang Chu, Clifford A Lowell
• Immunological reviews
• 2009

The adapter proteins DAP12 and FcRgamma associate with a wide spectrum of receptors in a variety of innate immune cells to mediate intracellular signaling pathways when their cognate receptor is… (More)

B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K.

• Minjian Ni, Alexander Macfarlane, Michelle Toft, Clifford A Lowell, Kerry S. Campbell, Jessica A. Hamerman
• Proceedings of the National Academy of Sciences…
• 2012

Toll-like receptors (TLRs) recognize pathogens and their components, thereby initiating immune responses to infectious organisms. TLR ligation leads to the activation of NF-κB and MAPKs through… (More)

Negative regulation of TLR signaling in myeloid cells--implications for autoimmune diseases.

• Jessica A. Hamerman, Jessica Pottle, Minjian Ni, Yantao He, Zhong-Yin Zhang, Jane H Buckner
• Immunological reviews
• 2016

Toll-like receptors (TLR) are transmembrane pattern recognition receptors that recognize microbial ligands and signal for production of inflammatory cytokines and type I interferon in macrophages and… (More)

Surfactant protein D is present in human tear fluid and the cornea and inhibits epithelial cell invasion by Pseudomonas aeruginosa.

• Minjian Ni, David J. Evans, Samuel B Hawgood, Ernst Anders, Robert A Sack, Suzanne M. J. Fleiszig
• Infection and immunity
• 2005

We have previously shown that human tear fluid protects corneal epithelial cells against Pseudomonas aeruginosa in vitro and in vivo and that protection does not depend upon tear bacteriostatic… (More)

Expression of surfactant protein D in human corneal epithelial cells is upregulated by Pseudomonas aeruginosa.

• Minjian Ni, Connie Tam, +4 authors Suzanne M. J. Fleiszig
• FEMS immunology and medical microbiology
• 2008

We reported previously that surfactant protein D (SP-D) was present in human tears and corneal epithelial cells, and that it contributed to tear fluid protection of those cells against Pseudomonas… (More)

Human tear fluid protects against Pseudomonas aeruginosa keratitis in a murine experimental model.

• Mary S F Kwong, David J. Evans, Minjian Ni, Brigitte A. Cowell, Suzanne M. J. Fleiszig
• Infection and immunity
• 2007

Pseudomonas aeruginosa keratitis is an acute sight-threatening infection. We previously reported that human tear fluid could protect individual human corneal epithelial cells in vitro against… (More)

Protein array characterization of bioactive proteins secreted by immortalized human corneal epithelium in response to pseudomonas constituents.

• Robert A Sack, Sonal Sathe, Ann R Beaton, Nancy Sinclair McNamara, Suzanne M. J. Fleiszig, Minjian Ni
• Current eye research
• 2009

PURPOSE To use protein arrays to delineate the spectrum of angiogenic bioactive protein modulators that might be secreted and up-regulated by the corneal epithelium in response to killed bacterial… (More)

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