Minika Majewska

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Minor histocompatibility (H) antigens create a barrier to the transplantation of organs and tissues between individuals matched for strong antigens, encoded by the major histocompatibility complex (MHC) in humans and by H-2 in mice. The male-specific antigen H-Y, which belongs to H antigens, provides a well-characterized system for studying graft rejection.(More)
There is strong evidence that melatonin possesses immunomodulatory activity. It has been shown that it enhances the immune response, acting as a pro-inflammatory agent. It is suggested that melatonin promotes Th1-mediated immune responses by upregulating IL-12 production by antigen presenting cells. In contrast, it has also been shown that melatonin can(More)
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