Minhua Xu

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The differential distribution of NMDA receptor subunit mRNAs in the developing mammalian cerebellum has been previously described. In this study, we investigated the temporal expression of NMDA receptor proteins in the postnatal murine cerebellum using antibodies specific for the NMDA zeta 1 and NMDA epsilon subunits. Our results showed a gradual increase(More)
Pituitary adenylyl cyclase-activating polypeptide (PACAP) can mediate growth hormone and gonadotropin release in teleost pituitary via PACAP receptors. In this study, the full-length cDNAs encoding PACAP and PACAP-related peptide (PRP) and the PACAP-specific receptor (PAC1-R) were cloned from the brain of darkbarbel catfish Pelteobagrus vachelli. The(More)
OBJECTIVES One of the major side effects of radiotherapy for treatments of the head and neck cancer is the radiation-induced dysfunction of salivary glands. The aim of the present study is to investigate the efficacy of deferoxamine (DFO) to restore the secretory function of radiation-damaged salivary glands in mice. METHODS DFO (50 mg/kg/d) was(More)
Relatively little is known regarding mitochondrial metabolism in neuronal differentiation of embryonic stem (ES) cells. By using a small molecule, present research has investigated the pattern of cellular energy metabolism in neural progenitor cells derived from mouse ES cells. Flavonoid compound 4a faithfully facilitated ES cells to differentiate into(More)
Premature ovarian failure and insufficiency are significant long-term side-effects of chemotherapy for female cancer patients. Recently, stem cell transplantation has been identified as a promising treatment for premature ovarian failure and insufficiency. We have previously demonstrated that human amniotic epithelial cells (hAECs) migrate into injured(More)
Follicular fluid is important for follicular development and oocyte maturation. Evidence suggests that follicular fluid is not only rich in proteins but cells. Besides oocytes, the follicular fluid contains granulosa, thecal, and ovarian surface epithelial cells, and both granulosa and thecal cells are well-characterized. However, epithelial cells in(More)
It has been known that the glutamate transmission system and N-methyl-D-aspartate receptor (NMDA-R) were possibly related to anxiety processes. Although anxiety symptom can be relieved by NMDA-R antagonists and partial agonists treatment, the functions of NMDA-R and its subunits in anxiety behaviors remain unclear. We used forebrain specific NR2B(More)
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