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Salmonella enterica serovars Typhi and Paratyphi A cause systemic infections in humans which are referred to as enteric fever. Multidrug-resistant (MDR) serovar Typhi isolates emerged in the 1980s, and in recent years MDR serovar Paratyphi A infections have become established as a significant problem across Asia. MDR in serovar Typhi is almost invariably(More)
BACKGROUND Previous studies dealing with the detection of enteroviral RNA in human endomyocardial biopsies have not differentiated between latent persistence of the enteroviral genome and active viral replication. Enteroviruses that are considered important factors for the development of myocarditis have a single-strand RNA genome of positive polarity that(More)
Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), remains a serious global health concern. Since their emergence in the mid-1970s multi-drug resistant (MDR) S. Typhi now dominate drug sensitive equivalents in many regions. MDR in S. Typhi is almost exclusively conferred by self-transmissible IncHI1 plasmids carrying a suite of(More)
High-resolution topography data acquired with LIDAR (Light Detection and Ranging) remote sensing technology have emerged as a fundamental tool for Earth science research. Because these acquisitions are often undertaken with federal and state funds at significant cost, it is important to maximize the impact of these geospatial data by providing online access(More)
Semantic Web Service, nowadays, is emerging as a solution for interoperating distributed applications on the WWW. Web service composition is the task of combining existing web services to yield a new service in order to achieve a desired goal. In this paper, we propose a formal approach to translate OWL-S web service descriptions into primitive and complex(More)
Escherichia coli sequence type 131 (E. coli ST131) is a recently emerged and globally disseminated multidrug resistant clone associated with urinary tract and bloodstream infections. Plasmids represent a major vehicle for the carriage of antibiotic resistance genes in E. coli ST131. In this study, we determined the complete sequence and performed a(More)
Fe 3 O 4 were synthesized nanoparticles by thermal decomposition method with oleic acid as the surfactant, and to make them suitable for aqueous environments, dopamine ligand exchange was carried out on the particles. The nanoparticle size and phase was quantified by transmission electron microscopy ͑TEM͒ and x-ray diffraction ͑XRD͒, respectively.(More)
Leveraging service-oriented architectures and taking advantage of the high-performance compute resources provided by XSEDE, we have developed standards-based web services to address the challenges associated with processing large volumes of high resolution topography data. These web services make results from community software packages and other(More)
This paper examines whether the US decision during World War I to violate enemy-owned patents-through compulsory licensing-discouraged invention. Estimates from a new data set of German patents indicate a 28 percent increase in invention. Controls for patent quality suggest that only a small share of the increase was due to lower quality, strategic patents.(More)