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To determine whether beta-endorphin might play a physiological role in regulating insulin secretion, we examined the rabbit pancreas for an endogenous source of beta-endorphin. Specific antibodies to beta-endorphin were used together with anti-insulin, anti-glucagon, and anti-somatostatin in single-labeled and double-labeled indirect immunofluorescence and(More)
Autoradiographic localization of 125I-labeled beta-endorphin binding in the rabbit pancreas demonstrated specific binding in the pancreatic islet cells. Binding was inhibited by (1) nonradioactive beta-endorphin, (2) the opioid antagonist naloxone, (3) the mu receptor agonists morphine and [D-Ala2, (Me)Phe4, Gly(ol)5]enkephalin, (4) the delta receptor(More)
  • Xiting Wang, Oufeng Tang, +4 authors Kai Zhong
  • 2017
Objective: To investigate the effect of crocin on the progression and generalized seizure of temporal lobe epilepsy in mice. Methods: Hippocampus rapid kindling model was established in C57BL/6J mice. The effects of crocin on seizure stage, afterdischarge duration (ADD), number of stimulation in each stage and final state, the incidence of generalized(More)
Spinal cord injury (SCI) leads to irreversible neuronal loss and ultimately leads to paralysis. Bone marrow derived mesenchymal stem cells (BMSCs) have been demonstrated to be an effective approach to treat SCI. The present study was designed to investigate the role of BMSCs in rats with spinal cord injury and in oxygen-glucose deprivation (OGD) treated(More)
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