Mingzhe Zhu

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BACKGROUND To investigate different responses to a high-fat/cholesterol diet and uncover their underlying genetic factors between C57BL/6J (B6) and DBA/2J (D2) inbred mice. METHODS B6 and D2 mice were fed a high-fat/cholesterol diet for a series of time-points. Serum and bile lipid profiles, bile acid yields, hepatic apoptosis, gallstones and(More)
NURR1 (also named as NR4A2) is a member of the steroid/thyroid hormone receptor family, which can bind to DNA and modulate expression of target genes. Previous studies have shown that NURR1 is essential for the nigral dopaminergic neuron phenotype and function maintenance, and the defects of the gene are possibly associated with Parkinson's disease (PD). In(More)
Heterogeneous high-performance computing (HPC) systems have been proposed as a power efficient alternative to traditional homogeneous systems. In heterogeneous HPC system, fast CPUs which have complex pipelines, high clock frequencies as well as high power consumption are combined with slow ones which have simple pipelines, low clock frequencies as well as(More)