Mingyu Shao

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It is commonly believed that crustacean haemocytes originate from a specialised haematopoietic tissue (HPT), whereas the differentiation relationship between HPT cells and circulating haemocytes is still not clearly understood. The HPT cells and haemocytes of Fenneropenaeus chinensis were characterised using morphological and histochemical methods. Three(More)
The identification of interactions between compounds and proteins plays an important role in network pharmacology and drug discovery. However, experimentally identifying compound-protein interactions (CPIs) is generally expensive and time-consuming, computational approaches are thus introduced. Among these, machine-learning based methods have achieved a(More)
Two novel elements (CFG1 and PYG1) of Mag lineage of Ty3/Gypsy retrotransposons were cloned from Zhikong scallop (Chlamys farreri) and Japanese scallop (Patinopecten yessoensis). The total length of the CFG1 element is 4826 bp, including 5′-LTR (192 bp), the entire ORF (4047 bp) and 3′-LTR (189 bp). The entire ORFs of both CFG1 and PYG1 elements are(More)
With the increase of available protein-protein interaction (PPI) data, more and more efforts have been put to PPI network modeling, and a number of models of PPI networks have been proposed. Roughly speaking, good models of PPI networks should be able to accurately describe PPI mechanisms, and thus reproduce the structures of PPI networks. With such models,(More)
MicroRNAs are known to play important roles in the transcriptional and post-transcriptional regulation of gene expression. While intensive research has been conducted to identify miRNAs and their target genes in various genomes, there is only limited knowledge about how microRNAs are regulated. In this study, we construct a pipeline that can infer the(More)
Exogenous sulfide can generally induce metabolic injuries in most organisms and even cause death. However, organisms inhabiting intertidal zones, hydrothermal vents, and cold seeps, can tolerate, metabolize, and utilize sulfide. In this study, both suppression subtractive hybridization and cDNA microarray analysis were employed to screen sulfide(More)
The vasa gene is a reliable germline marker to study the origin and development of germ cells and gonads, although the gene product (mRNA or protein) varies between different species. However, there has been little study on vasa genes in holothuroids to date. Here we determined the expression characteristics of the Apostichopus japonicus vasa gene (Aj-vasa)(More)
Protein-protein interaction (PPI) networks are crucial for organisms. Many research efforts have thus been devoted to the study on the topological properties and models of PPI networks. However, existing studies did not always report consistent results on the topological properties of PPI networks. Although a number of PPI network models have been(More)
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