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Recently, CRISPR/Cas9 technology has emerged as a powerful approach for targeted genome modification in eukaryotic organisms from yeast to human cell lines. Its successful application in several plant species promises enormous potential for basic and applied plant research. However, extensive studies are still needed to assess this system in other important(More)
— In this paper, we perform a rigorous analysis of EKF-based visual-inertial odometry (VIO) and present a method for improving its performance. Specifically, we examine the properties of EKF-based VIO, and show that the standard way of computing Jacobians in the filter inevitably causes inconsistency and loss of accuracy. This result is derived based on an(More)
BACKGROUND Glioblastomas (GBM) are comprised of a heterogeneous population of tumor cells, immune cells, and extracellular matrix. Interactions among these different cell types and pro-/anti-inflammatory cytokines may promote tumor development and progression. AIMS The objective of this study was to develop a cytokine-related gene signature to improve(More)
The bone morphogenetic family proteins (BMP) are phytogenetically conserved proteins, which are essential for embryonic development. The key regulatory subunit, the bone morphogenetic protein 4 (BMP4), is overexpressed and associated with tumor metastasis in a variety of cancers. However, the prognostic and molecular features of gliomas with BMP4 expression(More)
— All existing methods for vision-aided inertial navigation assume a camera with a global shutter, in which all the pixels in an image are captured simultaneously. However, the vast majority of consumer-grade cameras use rolling-shutter sensors, which capture each row of pixels at a slightly different time instant. The effects of the rolling shutter(More)
Chromosomal instability is a hallmark of human cancers and is closely linked to tumorigenesis. The prognostic value of molecular signatures of chromosomal instability (CIN) has been validated in various cancers. However, few studies have examined the relationship between CIN and glioma. Histone deacetylases (HDACs) regulate chromosome structure and are(More)
— We propose a particle filter-based algorithm for monocular vision-aided odometry for mobile robot localization. The algorithm fuses information from odometry with observations of naturally occurring static point features in the environment. A key contribution of this work is a novel approach for computing the particle weights, which does not require(More)