Mingxue Yang

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BACKGROUND Minimal stimulation in vitro fertilization (mini-in vitro fertilization) is an alternative in vitro fertilization treatment protocol that may reduce ovarian hyperstimulation syndrome, multiple pregnancy rates, and cost while retaining high live birth rates. OBJECTIVE We performed a randomized noninferiority controlled trial with a prespecified(More)
BACKGROUND The value of oocyte cryopreservation in older women remains controversial. The aim of this study was to report the oocyte freezing experience in women aged 40 and older at a single fertility center. FINDINGS One hundred fifty eight women (mean age 43.9 ± 0.2) who underwent minimal ovarian stimulation IVF were enrolled. IVF protocol included the(More)
OBJECTIVE The objective of this study was to assess the relationship between BMI and oocyte number and maturity in participants who underwent minimal stimulation (mini-) or conventional IVF. METHODS Participants who underwent their first autologous cycle of either conventional (n = 219) or mini-IVF (n = 220) were divided according to their BMI to analyze(More)
Mutations in mitochondrial DNA (mtDNA) are maternally inherited and can cause fatal or debilitating mitochondrial disorders. The severity of clinical symptoms is often associated with the level of mtDNA mutation load or degree of heteroplasmy. Current clinical options to prevent transmission of mtDNA mutations to offspring are limited. Experimental spindle(More)
BACKGROUND Haemophilus influenzae is a rare cause of intrauterine infection, with the potential to cause severe morbidity and mortality in the perinate. CASE An 18-year-old primigravida presented at 32 weeks' gestation with sudden-onset abdominal pain and abrupt cessation of fetal movements. Intrauterine fetal death was confirmed. At necropsy the fetus(More)
OBJECTIVE To compare cumulative live birth rate according to the rate of use of metaphase II (MII) oocytes in conventional ovarian stimulation protocols for in vitro fertilization (IVF) or intracytoplasmic sperm injection. METHODS In a cohort study, patients aged 18-38 years undergoing their first IVF treatment at one US center were enrolled between(More)
BACKGROUND An inverse relationship between oocyte efficiency and ovarian response was reported in conventional IVF. The purpose of this study was to report metaphase II (MII) oocyte efficiency according to oocyte yield in minimal/mild stimulation IVF (mIVF) and to assess whether oocyte yield affects live birth rate (LBR). METHODS Infertile women (n = 264)(More)
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