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Many practical engineering problems are naturally global optimization problems with complex constraints and local optimums. However, practicable and effective approaches for those constrained global optimization problems are still insufficient. A modified differential evolution algorithm is put forward for constrained global optimization problems in this(More)
—A robust archived differential evolution algorithm is put forward by means of embedding a flexibility processing operator and an efficiency processing operator based on original DE and ADE. A special constraint-handling mechanism based on dynamic penalty functions and fitness calculation of individuals is adopted in the proposed method to deal with various(More)
This paper has built a product model by UML and corresponding Product Schema. Then we have illuminated transmit mechanism of the product information by a dumbbell XML document. At last, we have pointed out the direction of the research. This research will provide a significative explore to the product data interchange between the members of virtual(More)
Deuterium-enriched and fluorine-substituted compounds have been widely applied in drug discovery due to their advantages in the studies of clinical pharmacokinetics and metabolic profiles. Herein we synthesized a library of deuterated and fluorine-substituted plinabulin derivatives, and all 15 D- or F-compounds were characterized by MS, $$^{1}\hbox {H}$$ 1(More)
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