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Bioinformatics is a discipline that uses computational tools and computer technologies to model, analyze, present, and visualize biological data. In this paper, we discuss the design of a bioinformatics track within the computer science curriculum at Winona State University's Rochester campus. We also developed a bioinformatics course and used it as a(More)
  • Mingrui Zhang
  • 2013
In the error control system, in order to ensure the validity and reliability of data transmission, people usually use error control. Automatic retransmission request (ARQ), which restores error messages by requesting receivers to send error data messages again is a method for processing channel errors in communication system. There are three basic ARQ ways,(More)
Segmentation of an image into regions and the labeling of the regions is a challenging problem. In this paper, an approach that is applicable to any set of multifeature images of the same location is derived. Our approach applies to, for example, medical images of a region of the body; repeated camera images of the same area; and satellite images of a(More)
Lung adenocarcinoma is the most common type of primary lung cancer. The purpose of this study was to delineate gene expression patterns for survival prediction in lung adenocarcinoma. Gene expression profiles of 82 (discovery set) and 442 (validation set 1) lung adenocarcinoma tumor tissues were analyzed using a systems biology-based network approach. We(More)
A knowledge-guided approach to automatic classification of Coastal Zone Color images of the West Florida Shelf is described. The approach is used to identify red tides on the West Florida Shelf, as well as areas with high concentration of dissolved organic matter such as a river plume found seasonally along the West Florida coast over the middle of the(More)
The Computer Science Department at Winona State University revised its curriculum to include an interdisciplinary approach adapted to the study of computer science. The new curriculum consists of a traditional Computer Science option and an Applied Computer Science option consisting of four separate tracks, namely: bioinformatics, computer information(More)
To engage a broader audience in computer science, we have developed a set of curriculum units embedded with computer science concepts for K-12 science education. We chose bioinformatics as a vehicle to deliver these units. Our curriculum development cycle began with the identification of a set of computer science concepts which are potentially relevant to(More)
One of the major challenges in unsupervised clustering is the lack of consistent means for assessing the quality of clusters. In this paper, we evaluate several validity measures in fuzzy clustering and develop a new measure for a fuzzy c-means algorithm which uses a Pearson correlation in its distance metrics. The measure is designed with within-cluster(More)
BACKGROUND We sought to build prognostic nomograms and identify novel prognostic factors in small-cell lung cancer (SCLC) incorporating both clinical data and peripheral blood markers. METHODS We analyzed 938 patients with SCLC (555 extensive stage SCLC [ES-SCLC] and 383 limited stage SCLC [LS-SCLC]) diagnosed between 1997 and 2012 from a single(More)