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Accurate gene model annotation of reference genomes is critical for making them useful. The modENCODE project has improved the D. melanogaster genome annotation by using deep and diverse high-throughput data. Since transcriptional activity that has been evolutionarily conserved is likely to have an advantageous function, we have performed large-scale(More)
This paper addresses the problem of pilot reuse among the inter-cell user terminals (UTs) for massive multi-input multi-output (MIMO) transmission. Firstly, we derive the closed-form expression of the non-asymptotic downlink (DL) achievable rate by using the second-order channel statistical information. Based on this, we present the spatial orthogonality(More)
A clinical pathway implements best medical practices and represents sequencing and timing of interventions by clinicians for a particular clinical presentation. We used a Bayesian belief network (BBN) to model a clinical pathway for radical prostatectomy and to categorize patient's length of stay (LOS) as being met or delayed given the patient's outcomes(More)
There has been a renewed interest in investigating the role of stabilizing selection acting on genome-wide traits such as codon usage bias. Codon bias, when synonymous codons are used at unequal frequencies, occurs in a wide variety of taxa. Standard evolutionary models explain the maintenance of codon bias through a balance of genetic drift, mutation and(More)
A clinical pathway represents sequencing and timing of interventions by clinicians, nurses and other healthcare professionals for a particular clinical presentation. It is designed to minimize delays and resource utilizations and to maximize the quality of tertiary care. A pathway is used to monitor and control patient’s progress that is measured according(More)
BACKGROUND Epithelial ovarian cancer (EOC) is the deadliest gynecological malignancy, and evidence is accumulating on how molecular markers may be associated with the origin and process of EOC. Sam68 (Src-associated in mitosis, of 68 kD), is a K homology domain RNA-binding protein that has been investigated as a risk factor in multiple types of tumors. The(More)