Minghui Shen

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Liver tumorigenesis frequently causes insulin resistance which may be used as an independent risk factor for evaluation of survival and post-surgery relapse of liver cancer patients. In the present study, HepG2/IR, an insulin resistant HepG2 cell line, was established by exposing HepG2 cells to 0.5 µmol/l of insulin for 72 h, and comparison of HepG2/IR with(More)
Widespread hypomethylation of DNA and regional hypermethylation, including tumor suppressor regions, have been demonstrated in several human cancers. Since a highly heterogeneous array of genetic anomalies have been associated with breast cancer, we examined several chromosomal hot spots for abnormal methylation patterns. Low-levels of increased methylation(More)
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