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BACKGROUND Primary spontaneous pneumothorax (PSP) or pulmonary cysts is one of the manifestations of Birt-Hogg-Dube syndrome (BHDS) that is caused by heterozygous mutations in FLCN gene. Most of the mutations are SNVs and small indels, and there are also approximately 10 % large intragenic deletions and duplications of the mutations. These molecular(More)
While founded on the situation calculus, current implementations of Golog are mainly based on the closed-world assumption or its dynamic versions or the domain closure assumption. Also, they are almost exclusively based on regression. In this paper, we propose a first-order interpreter for knowledge-based Golog with sensing based on exact progression and(More)
Streptococcal heme binding protein (Shp) is a surface protein of the heme acquisition system that is an essential iron nutrient in Group A Streptococcus (GAS). Here, we tested whether Shp immunization protects mice from subcutaneous infection. Mice were immunized subcutaneously with recombinant Shp and then challenged with GAS. The protective effects(More)
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