Mingfei Zhang

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Melittin, the major component of the European bee venom, is a potential anticancer candidate due to its lytic properties. However, in vivo applications of melittin are limited due to its main side effect, hemolysis, especially when applied through intravenous administration. The polyethylene glycol-stabilized lipid disk is a novel type of nanocarrier, and(More)
The rapid proliferation of glioma relies on vigorous angiogenesis for the supply of essential nutrients; thus, a radical method of antiglioma therapy should include blocking tumor neovasculature formation. A phage display selected heptapeptide, the glioma-initiating cell peptide GICP, was previously reported as a ligand of VAV3 protein (a Rho GTPase guanine(More)
This paper presents a system framework taking the advantages of the WSN for the real-time monitoring on the water quality in aquaculture. We design the structure of the wireless sensor network to collect and continuously transmit data to the monitoring software. Then we accomplish the configuration model in the software that enhances the reuse and facility(More)
A novel p-n junction photocatalyst of Bi4Ti3O12 nanofibers-BiOI nanosheets has been fabricated through a simple and economical technique of electrospinning combined with a successive ionic layer adsorption and reaction (SILAR) process. The products are characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray(More)
Organic acids are a major index of fresh fruit marketing properties. However, the genetic effects on the organic acid level in postharvest citrus fruit still remain unknown. Here, we used the fruits of about 40 lines in a hybrid population (high-acid "HB Pumelo" × low-acid "Fairchild") to analyze the organic acid metabolism of postharvest citrus fruit. A(More)
Considering the complex of decision-making process of rainbow trout feeding, a rainbow trout feeding decision support system is built by integrating case-based reasoning and rule-based reasoning with XML. This paper describes the theory of hybrid reasoning, and several experiment results with their own interpretation. The web based feeding decision support(More)
Malignant glioma, the most frequent and aggressive central nervous system (CNS) tumor, severely threatens human health. One reason for its poor prognosis and short survival is the presence of the blood-brain barrier (BBB) and blood-brain tumor barrier (BBTB), which restrict the penetration of therapeutics into the brain at different stages of glioma.(More)
Antagonizing MDM2 and MDMX to activate the tumor suppressor protein p53 is an attractive therapeutic paradigm for the treatment of glioblastoma multiforme (GBM). However, challenges remain with respect to the poor ability of p53 activators to efficiently cross the blood-brain barrier and/or blood-brain tumor barrier and to specifically target tumor cells.(More)
To comprehensively analyze the effects of salicylic acid (SA) on the storability of Satsuma mandarin (Citrus unshiu), fruits were treated with 2mM SA. The disease incidence of control/SA-treated fruit at 50d and 120d after treatment was 23.3%/10% and 67.3%/23.3%, respectively, suggesting that SA treatment can significantly reduce the rot rate of postharvest(More)
As the most aggressive brain tumor, chemotherapy of malignant glioma remains to be extremely challenging in clinic. The blood-brain barrier (BBB) and blood-brain tumor barrier (BBTB) are physiological and pathological barriers preventing therapeutic drugs from reaching the glioma region. In addition, vasculogenic mimicry (VM) formed by invasive glioma cells(More)
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