Ming-sheng Huang

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OBJECTIVE To investigate the relationship between ApoE epsilon4 allele and hippocampal atrophy in patients with AD. METHODS Using MRI-based volumetry technique and PCR-FRLP, the hippocampal volume and ApoE genotype of 34 AD patients were examined, and the difference in hippocampal volume between the ApoE epsilon4 positive AD group (n=17) and the ApoE(More)
OBJECTIVE To investigate the effects of bilaterally injection of amyloid-beta (25-35) peptide (APP25-35) to the nbM areas on the spatial learning and memory in rats. METHODS Ten experimental rats were injected bilaterally in the areas of nbM with AbetaP25-35. Another ten rats in the sham-injection group were injected with normal saline. The spatial memory(More)
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