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MicroRNA-200c inhibits the metastasis of non-small cell lung cancer cells by targeting ZEB2, an epithelial-mesenchymal transition regulator.
MicroRNAs (miRs) have been demonstrated to regulate various biological processes in human cancer, including non-small cell lung cancer (NSCLC). However, little evidence has been provided regardingExpand
Overexpression of Long Non-Coding RNA TUG1 Promotes Colon Cancer Progression
Background Colon cancer is one of the most prevalent and deadly cancers worldwide. It is still necessary to further define the mechanisms and explore therapeutic targets of colon cancer.Expand
Expression of Cytosolic Phospholipase A2 (cPLA2)-Arachidonic Acid (AA)-Cyclooxygenase-2 (COX-2) Pathway Factors in Lung Cancer Patients and Its Implication in Lung Cancer Early Detection and Prognosis
Background The aim of this study was to elucidate the involvement of cPLA2-AA-COX-2 pathway factors and their potential role in lung cancer early diagnosis and prognosis. Material/Methods We selectedExpand
Nitidine chloride inhibits proliferation and induces apoptosis in colorectal cancer cells by suppressing the ERK signaling pathway
Nitidine chloride (NC) is a natural bioactive phytochemical alkaloid that has displayed anticancer activity in various types of cancer. However, no evidence has been reported for the direct effect ofExpand
Upregulation of miR-125b is associated with poor prognosis and trastuzumab resistance in HER2-positive gastric cancer
Gastric cancer is one of the most common types of human cancer associated with a poor prognosis. MicroRNAs (miRs), a class of non-coding RNAs that are 18–25 nucleotides in length, act as keyExpand
miR-218 inhibits acute promyelocytic leukemia cell growth by targeting BMI-1.
Acute promyelocytic leukemia (APL) is a subtype of acute myelocytic leukemia. Previous studies have reported a number of functions and therapeutic roles of microRNAs (miRs) in APL, and have suggestedExpand
Inhibition of PLA2G4A Reduces the Expression of Lung Cancer-Related Cytokines.
Phospholipase A2-IVA (PLA2G4A) is the most abundant subtype of cytoplasmic phospholipase A2 (cPLA2) and is an important enzyme in tumor development. Our study aimed to explore the role of PLA2G4A inExpand
LncRNA 00152 promotes the development of hepatocellular carcinoma by activating JAK2/STAT3 pathway.
OBJECTIVE The aim of this study was to explore the regulatory role of lncRNA 00152 and JAK2/STAT3 pathway in the pathogenesis of hepatocellular carcinoma (HCC), and to investigate the possibleExpand
Long non-coding RNA H19 promotes proliferation of Hodgkin's lymphoma via AKT pathway.
PURPOSE To explore whether lncRNA (Long non-coding RNA) H19 could promote the development of Hodgkin's lymphoma (HL) by regulating cell proliferation via AKT pathway. METHODS H19 expressions in 60Expand
MiR-296 promotes colorectal cancer cells growth through regulating NF-κB
Tumor reduced people’s quality of life. Colon cancer is hard to cure. MicroRNA abnormal expression induces oncogenesis. We intended to explore miR-296 role in colorectal cancer development. MiR-296Expand