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Exposure to ozone, which is a major component of air pollution, induces a form of asthma that occurs in the absence of adaptive immunity. Although ozone-induced asthma is characterized by airway neutrophilia, and not eosinophilia, it is nevertheless associated with airway hyperreactivity (AHR), which is a cardinal feature of asthma. Because AHR induced by(More)
The human interface of a Caterpillar 325FB feller-buncher was modiied to allow the operator to use i a 5-DOF joystick, and ii a 6-DOF magnetically-levitated joystick with stiiness feedback. While the operator commanded the velocity of the endpoint, an onboard computer system managed total system power, solved the inverse kinematics, servoed the joint(More)
—Small-cell systems based on cloud radio access network (cloud-RAN) architecture have been proposed as promising solutions to meet the capacity demand of the future wireless access networks in a cost-effective and power-efficient way. High-speed and scalable backhaul links between the centralized baseband processing units (BBUs) and the remote antenna units(More)
—Today's enterprise WLAN is facing challenges as the rapid growth of user scale and traffic load. Users often experience slow or even intermittent connection in crowded area. This is mainly due to the interference among densely-deployed access points (APs). In this paper, we took advantages of the emerging idea of SDN and OpenFlow technology to mitigate(More)
We have developed pLink, software for data analysis of cross-linked proteins coupled with mass-spectrometry analysis. pLink reliably estimates false discovery rate in cross-link identification and is compatible with multiple homo- or hetero-bifunctional cross-linkers. We validated the program with proteins of known structures, and we further tested it on(More)
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Veliparib, a potent, oral PARP inhibitor, potentiates the antitumor activity of radiation therapy and crosses the blood-brain barrier. This was a phase 1 dose-escalation study evaluating the safety, and secondarily the antitumor activity of veliparib in combination with whole brain radiation therapy (WBRT) in patients with brain metastases, in order to(More)