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Lindenane sesquiterpenoid dimers from Chloranthus japonicus inhibit HIV-1 and HCV replication.
Phytochemical investigation on the whole plant of Chloranthus japonicus (Chloranthaceae) led to the isolation and identification of three new lindenane-type sesquiterpenoid dimers, chlorajaponilidesExpand
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Discovery of a semi-synthesized cyclolignan as a potent HIV-1 non-nucleoside reverse transcriptase inhibitor
  • J. Guo, Ming-Yu Ba, +4 authors Y. Guo
  • Chemistry, Medicine
  • Journal of Asian natural products research
  • 2 January 2019
Abstract Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are essential components of highly active antiretroviral therapy (HAART) for human immunodeficiency virus type 1 (HIV-1) infection.Expand
  • 2
Discovery, synthesis, and optimization of an N-alkoxy indolylacetamide against HIV-1 carrying NNRTI-resistant mutations from the Isatis indigotica root
  • C. Xu, Yijing Xin, +5 authors J. Shi
  • Chemistry, Medicine
  • European Journal of Medicinal Chemistry
  • 22 January 2020
Abstract From an aqueous decoction of the traditional Chinese medicine “ban lan gen” (the Isatis indigotica root), an antiviral natural product CI - 39 was isolated as an NNRTI (non-nucleosideExpand
  • 2
[Mechanism and action characteristics studies of a quinoxalinone compound against HIV-1 replication].
This study is to investigate the mechanism and action characteristics of 6-chloro-3-methyl-4-(2-methyoxycarbonylthiophene-3-sulfonyl)-3, 4-dihydroquinoxa-lin-2-(1 H)-one (XU07011) against HIV-1Expand