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MicroRNAs (miRNAs) are postulated to be important regulators in cancers. Here, we report a genome-wide miRNA expression analysis in 52 acute myeloid leukemia (AML) samples with common translocations, including t(8;21)/AML1(RUNX1)-ETO(RUNX1T1), inv(16)/CBFB-MYH11, t(15;17)/PML-RARA, and MLL rearrangements. Distinct miRNA expression patterns were observed for(More)
STUDY DESIGN A retrospective study of surgical outcome of 33 patients with irreducible atlantoaxial dislocation (IAAD). OBJECTIVE To evaluate the safety efficacy of one stage anterior release and posterior fixation and fusion to reduce and stabilize IAAD. SUMMARY OF BACKGROUND DATA The traditional treatment of symptomatic IAAD is ventral decompression(More)
As Chinese is written without orthographical word boundaries (i.e., spaces), it is unclear whether saccade targets are selected on the basis of characters or words and whether saccades are aimed at the beginning or the centre of words. Here, we report an experiment where 30 Chinese readers read 150 sentences while their eye movements were monitored. They(More)
The high affinity nitrate transport system (HATS) plays an important role in rice nitrogen acquisition because, even under flooded anaerobic cultivation when NH(4)(+) dominates, significant nitrification occurs on the root surface. In the rice genome, four NRT2 and two NAR2 genes encoding HATS components have been identified. One gene OsNRT2.3 was mRNA(More)
In compressive sensing (CS), the goal is to recover signals at reduced sample rate compared to the classic Shannon-Nyquist rate. However, the classic CS theory assumes the measurements to be real-valued and have infinite bit precision. The quantization of CS measurements has been studied recently and it has been shown that accurate and stable signal(More)
This article studies the problem of image restoration of observed images corrupted by impulse noise and mixed Gaussian impulse noise. Since the pixels damaged by impulse noise contain no information about the true image, how to find this set correctly is a very important problem. We propose two methods based on blind inpainting and 0 minimization that can(More)
Insulin-like growth factor 1 (IGF-1) is a potent mitogenic protein which can enhance the osteogenic differentiation of periodontal ligament (PDL) fibroblasts. However, it remains unclear whether IGF-1 can stimulate the osteogenic differentiation and osteogenesis of human periodontal ligament stem cells (PDLSCs). In this study, STRO-1+ PDLSCs were isolated(More)
A cofactor regeneration system for enzymatic biosynthesis was constructed by coexpressing a carbonyl reductase from Pichia stipitis and a glucose dehydrogenase from Bacillus megaterium in Escherichia coli Rosetta (DE3) PlySs. Transformants containing the polycistronic plasmid pET-PII-SD2-AS1-B exhibited an activity of 13.5 U/mg protein with(More)
BACKGROUND A proportion of glioblastoma stemlike cells (GSCs) expressing endothelial cell marker CDH5 (vascular-endothelial-cadherin or CD144) can transdifferentiate into endothelial cells and form blood vessels. However, the implications of CDH5 expression in gliomas and how it is regulated in GSCs remain to be clarified. METHODS The mRNA and protein(More)
The mutations in the gene encoding copper-zinc superoxide dismutase (SOD1) cause approximately 20% cases of familial amyotrophic lateral sclerosis (FALS), characterized by selective loss of motor neurons. Mutant SOD1 forms inclusions in tissues from FALS patients. However, the precise mechanism of the accumulation of mutant SOD1 remains unclear. Here we(More)