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PURPOSE To investigate the utility of an automated perfusion-weighted MRI (PWI) method for estimating cerebral blood flow (CBF) based on localized arterial input functions (AIFs) as compared to the standard method of manual global AIF selection, which is prone to deconvolution errors due to the effects of delay and dispersion of the contrast bolus. (More)
BACKGROUND The identification of hepatitis E virus (HEV) from rabbits motivated us to assess the possibility of using rabbits as a non-human primate animal model for HEV infection and vaccine evaluation. METHODOLOGY/PRINCIPAL FINDINGS First, 75 rabbits were inoculated with seven strains of genotypes 1, 3, 4, and rabbit HEV, to determine the appropriate(More)
PURPOSE To investigate a previously developed method for perfusion-weighted MRI (PWI) cerebral blood flow (CBF) estimation that uses local arterial input functions (AIFs) in stroke patients, and determine its ability to correct delay and/or dispersion (D/D) errors. MATERIALS AND METHODS Analysis was performed on dynamic susceptibility contrast data from(More)
Cardiac hypertrophy is a well-established risk factor for cardiovascular morbidity and mortality. Activation of G(q/11)-mediated signaling is required for pressure overload-induced cardiomyocyte (CM) hypertrophy to develop. We previously showed that among Regulators of G protein Signaling, RGS2 selectively inhibits G(q/11) signaling and its hypertrophic(More)
BACKGROUND The Internet is increasingly being applied in health education worldwide; however there is little knowledge of its use in Chinese higher education institutions. The present study provides the first review and highlights the deficiencies and required future advances in Chinese Internet-based health education. METHODS Two authors independently(More)
Levels of melatonin in rabbit eye tissues were detected by radioimmunoassay. Solutions of met-enkephalin, leu-enkephalin, alpha-endorphin and beta-endorphin were given topically. Met-Enkephalin and alpha-endorphin lowered levels of melatonin in the iris, iris root-ciliary body, retina and choroid; leu-enkephalin raised levels in the retina and lowered them(More)
An artificial compound eye system is the bionic system of natural compound eyes with much wider field-of-view, better capacity to detect moving objects and higher sensitivity to light intensity than ordinary single-aperture eyes. In recent years, renewed attention has been paid to the artificial compound eyes, due to their better characteristics inheriting(More)
Because of the long acquisition time and spin-echo planar imaging sequence, diffusion weight magnetic resonance image (DWI) should be denoised effectively to ensure the follow-up applications. The commonly used denoising methods which induced from gray level image lack the use of the specific information from multiple magnitude directions. This paper,(More)
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