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A new LDA-based face recognition system is presented in this paper. Linear discriminant analysis (LDA) is one of the most popular linear projection techniques for feature extraction. The major drawback of applying LDA is that it may encounter the small sample size problem. In this paper, we propose a new LDA-based technique which can solve the small sample(More)
Due to the importance of protein phosphorylation in cellular control, many researches are undertaken to predict the kinase-specific phosphorylation sites. Referred to our previous work, KinasePhos 1.0, incorporated profile hidden Markov model (HMM) with flanking residues of the kinase-specific phosphorylation sites. Herein, a new web server, KinasePhos 2.0,(More)
One major task in the post-genome era is to reconstruct proteomic and genomic interacting networks using high-throughput experiment data. To identify essential nodes/hubs in these interactomes is a way to decipher the critical keys inside biochemical pathways or complex networks. These essential nodes/hubs may serve as potential drug-targets for developing(More)
Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful information to understand how biological systems work. Therefore, detecting functional modules is an important research topic in the post-genome era. One of functional module detecting methods is(More)
Structural analysis is useful in elucidating structural features responsible for enhanced thermal stability of proteins. However, due to the rapid increase of sequenced genomic data, there are far more protein sequences than the corresponding three-dimensional (3D) structures. The usual sequence-based amino acid composition analysis provides useful but(More)
In this paper, we present a system that extracts and generalizes terms from Internet documents to represent classification knowledge of a given class hierarchy. We propose a measurement to evaluate the importance of a term with respect to a class in the class hierarchy, and denote it as support. With a given threshold, terms with high supports are sifted as(More)
Let G = (V; E) be a /nite and undirected graph without loops and multiple edges. An edge is said to dominate itself and any edge adjacent to it. A subset D of E is called a perfect edge dominating set if every edge of E \ D is dominated by exactly one edge in D and an e cient edge dominating set if every edge of E is dominated by exactly one edge in D. The(More)
Network is a useful way for presenting many types of biological data including protein-protein interactions, gene regulations, cellular pathways, and signal transductions. We can measure nodes by their network features to infer their importance in the network, and it can help us identify central elements of biological networks. We introduce a novel(More)