Ming-Sheng Huang

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BACKGROUND The aim of this study was to explore the characteristics and efficacy of psychoeducational family intervention for persons with schizophrenia in rural China. METHODS A cluster randomised controlled trial of psychoeducational family intervention for families experiencing schizophrenia (three groups, 326 cases) was conducted in Xinjin County,(More)
OBJECTIVE To study the neuron apoptosis induced by i.p 3,4-methylenedioxy methamphetamine (MDMA) and the expression of apoptosis-related factors in rat brain. METHODS Twenty rats were divided into 4 groups. In group A, the rats were injected intraperitoneally with single dosage of saline, while the rats of group B, C, D were injected i.p with MDMA in(More)
3,4-Methylenedioxymethamphetamine (MDMA) is a substituted amphetamine with stimulating and hallucinogenic properties. Since MDMA induces "ecstasy" it is extensively used as a "recreational" drug. It has been well established that MDMA is neurotoxic and can result in long-term degeneration of cerebral 5-hydroxytryptamine (5-HT) nerve terminals in many(More)
OBJECTIVE To investigate the relationship between ApoE epsilon4 allele and hippocampal atrophy in patients with AD. METHODS Using MRI-based volumetry technique and PCR-FRLP, the hippocampal volume and ApoE genotype of 34 AD patients were examined, and the difference in hippocampal volume between the ApoE epsilon4 positive AD group (n=17) and the ApoE(More)
OBJECTIVE To assess the characteristics and factors affecting course of schizophrenia in a Chinese rural area. METHOD An epidemiological investigation was conducted to identify all the patients with schizophrenia among 149 231 people in Xinjin County, Chengdu. RESULTS The total prevalence of schizophrenia was 4.13 per 1000 population. Males had an(More)
OBJECTIVE To investigate the effects of bilaterally injection of amyloid-beta (25-35) peptide (APP25-35) to the nbM areas on the spatial learning and memory in rats. METHODS Ten experimental rats were injected bilaterally in the areas of nbM with AbetaP25-35. Another ten rats in the sham-injection group were injected with normal saline. The spatial memory(More)
OBJECTIVE Establishing a long-term neurotoxic model to explore the mechanism of neurotoxicity of 3,4-methylenedioxymethamphetamine (MDMA) and the putative protection conferred by Vit C against oxidative stress harm. METHODS Male Wistar rats were randomly assigned to control group (A) and MDMA treatment groups(B, C, D, E). Rats of group B were given MDMA(More)
Relatively little is known about the different characteristics of non-institutionalized geriatric and younger subjects with schizophrenia. This study compared demographic and clinical characteristics of all the geriatric, middle-age and young subjects with schizophrenia living in a Chinese rural community. Geriatric (age >/= 65 years) (N = 51), middle-age(More)
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