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In this review, we examine the current status of stroke epidemiology, prevention, and management strategies in mainland China. The main findings suggested that total age-adjusted incidence of first-ever stroke in China is not very different from that in developed countries. Stroke incidence, mortality, and prevalence varied widely among different regions(More)
In this paper, we present a patch-based regression framework for addressing the human age and head pose estimation problems. Firstly, each image is encoded as an ensemble of orderless coordinate patches, the global distribution of which is described by Gaussian mixture models (GMM), and then each image is further expressed as a specific distribution model(More)
We describe a large audio-visual speech corpus recorded in a car environment, as well as the equipment and procedures used to build this corpus. Data are collected through a multi-sensory array consisting of eight microphones on the sun visor and four video cameras on the dashboard. The script for the corpus consists of four categories: isolated digits,(More)
OBJECTIVE Zinc ions are essential for the formation of hexameric insulin and hormone crystallization. A nonsynonymous single nucleotide polymorphism rs13266634 in the SLC30A8 gene, encoding the secretory granule zinc transporter ZnT8, is associated with type 2 diabetes. We describe the effects of deleting the ZnT8 gene in mice and explore the action of the(More)
This paper presents a new region-based active contour model in a variational level set formulation for image segmentation. In our model, the local image intensities are described by Gaussian distributions with different means and variances. We define a local Gaussian distribution fitting energy with a level set function and local means and variances as(More)
Run-time Partial Reconfiguration (PR) speed is significant in applications especially when fast IP core switching is required. In this paper, we propose to use Direct Memory Access (DMA), Master (MST) burst, and a dedicated Block RAM (BRAM) cache respectively to reduce the reconfiguration time. Based on the Xilinx PR technology and the Internal(More)
We propose a five-layer hierarchical space-time model (HSTM) for representing and searching human actions in videos. From a feature point of view, both invariance and selectivity are desirable characteristics, which seem to contradict each other. To make these characteristics coexist, we introduce a coarse-to-fine search and verification scheme based on the(More)
Permanent neonatal diabetes mellitus (PNDM) is a rare disorder usually presenting within 6 months of birth. Although several genes have been linked to this disorder, in almost half the cases documented in Italy, the genetic cause remains unknown. Because the Akita mouse bearing a mutation in the Ins2 gene exhibits PNDM associated with pancreatic beta cell(More)
The calpains are a class of cellular cysteine proteases that require calcium and are functionally active at neutral pH. Calpain activation can take place in two modes: controlled activation under physiological conditions (in which only a few molecules of calpain are activated per cell), and hyperactivation under pathological conditions that involve(More)