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A Role for Innexin2 and Innexin3 Proteins from Spodoptera litura in Apoptosis
This study showed that Sf9 and Spli221 cells undergo low level apoptosis under normal culture conditions, but not Hi5 cells, which suggests that innexon-promoted apoptosis may be involving the PI3K/Akt signaling pathway.
A Point Cloud Simplification Method Based on Modified Fuzzy C-Means Clustering Algorithm with Feature Information Reserved
The results show that the new proposed algorithm can not only effectively improve the precision of point cloud simplification but also reserve the accuracy of part features.
Down-regulated expression of OPCML predicts an unfavorable prognosis and promotes disease progression in human gastric cancer
Down-regulated OPCML expression might serve as an independent predictor for unfavorable prognosis of patients, and the biological behavior supports its role as a tumor suppressor in gastric cancer.
A Transcriptome Analysis Suggests Apoptosis-Related Signaling Pathways in Hemocytes of Spodoptera litura After Parasitization by Microplitis bicoloratus
A new RNAseq-based comparative analysis of the hemocytes transcriptomes of non-parasitized and parasitized S. litura hemocytes suggests that M. bicoloratus parasitism may regulate host mitochondria to trigger internucleosomal DNA fragmentation and facilitates the identification of immunosuppression-related genes.
Inhibition of translation initiation factor eIF4A is required for apoptosis mediated by Microplitis bicoloratus bracovirus.
- Shu-Mei Dong, Ji-Hui Cui, Kaijun Luo
- BiologyArchives of insect biochemistry and physiology
- 20 September 2017
Findings suggested that MbBV inhibited the expression of eIF4A, which was required for apoptosis mediated by MbV, which will contribute to biological pest control and enhance the understanding of molecular mechanisms underlying polydnavirus-parasitoid-host interaction.
Angiotensin II upregulates cyclophilin A by enhancing ROS production in rat cardiomyocytes
It was identified that Ang II enhanced the production of ROS in rat cardiomyocytes and was primarily dependent on the angiotensin type 2 receptor (AT2R), not the type 1 receptor, providing an insight into the role of the AT2R signaling pathway in Ang II-induced myocardial hypertrophy.
A polydnaviral genome of Microplitis bicoloratus bracovirus and molecular interactions between the host and virus involved in NF-κB signaling
Data show that viral IκB-like transcription does not inhibit host NF-κB/IκB expression, suggesting that transcription of these genes might be regulated by different mechanisms.
Strategy for the determination of unsteady aerodynamic forces on elongated bodies in grid-generated turbulent flow
Arachidonate 12-lipoxygenase may serve as a potential marker and therapeutic target for prostate cancer stem cells.
Multiple lines of evidence support the possibility that 12-LOX may serve as a unique marker and therapeutic target for PCa SCs.