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Basilar membrane (BM) noise, measured as a velocity signal under the quiet acoustic condition, was investigated in the guinea pig. The cochleas of anesthetized young healthy guinea pigs were surgically exposed and a hole was made on the lateral wall of the scala tympani of the first cochlear turn for visualization of the BM and measurement of the BM(More)
Basilar membrane (BM) velocity responses were measured in the presence of olivocochlear bundle (OCB) stimulation. Frequency threshold tuning curves (FTCs) were derived from tone-evoked input-output (I/O) functions. Efferent nerve activation produced decreases in velocity amplitude for frequencies around best frequency (BF) at low stimulus levels with little(More)
Electric current applied to the cochlea can evoke in situ electromotile responses of the organ of Corti. These nonsound-generated responses can give insight into the mechanics of the organ as the putative forces produced by outer hair cells (OHC) must couple to the modes of vibration of the basilar membrane (BM). In this study, platinum-iridium wire(More)
OBJECTIVE To estimate correlation between phonetically balanced maximum (PB max) and pure tone auditory threshold in auditory neuropathy (AN) patients. METHODS One hundred and six AN patients were identified using multiple criteria including PB max, a metric for speech recognition, pure tone auditory threshold, acoustic emission test, distortion products(More)
  • M Guo
  • 2001
OBJECTIVE To explore the effects of direct current on vibration of cochlear basilar membrane. METHODS A small hole with a diameter about 0.4 mm, which had the distance of 2.4 mm from round window niche, was made on cochlear basic turn of guinea pig for measuring the velocity of basilar membrane in vivo. On the superior and inferior edge of the measuring(More)
To investigate the electromotility of basilar membrane (BM) of guinea pigs in vivo, a couple of Platinum-iridium wire electrodes were placed into holes drilled in the scala vestibuli and scala tympani on the basal turn of cochlea separately. The organ of Corti was stimulated with rectangular direct current pulses. The displacement and velocity of BM were(More)
  • M Guo
  • 1990
Correlation function and power spectrum analyses were made for ABR of 20 normal ears and 14 ears with retrocochlear lesions. Power spectrum of normal ABR had three peaks, F0, F1 and F2; their frequencies being 125, 552.5, 967.5Hz respectively; the spectrographic shapes were of good similitude. The curve of cross correlation function in normal ABR was(More)
  • M Guo
  • 1989
A method which can record and plot the electrocochleogram (ECochG) and auditory brainstem response (ABR) simultaneously with the same tracing was studied. The results demonstrated that the ECochG waves obtained by our method and that recorded alone were very similar. The -SP/AP values and the latencies of ABR obtained by those two methods had no(More)
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