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Sperm chromatin structure assay parameters are not related to fertilization rates, embryo quality, and pregnancy rates in in vitro fertilization and intracytoplasmic sperm injection, but might be
TLDR
Neither DFI nor HDS scores can provide independent information about embryo quality, fertilization, and PRs for infertility patients undergoing ART, and the potential adverse effect of sperm DNA damage on the quality of postimplantation embryo and spontaneous abortion should be a concern. Expand
Poor Response of Ovaries with Endometrioma Previously Treated with Cystectomy to Controlled Ovarian Hyperstimulation
TLDR
Surgery for ovarian endometrioma may damage ovarian reserve and potentially results in poor ovarian response to COH, compared to the response of the contralateral normal ovary in the same individual. Expand
Sperm morphology analysis using strict criteria as a prognostic factor in intrauterine insemination.
TLDR
IUI is a reasonable first-line therapy for patients with sperm morphology >4% normal forms, while couples with <4%normal forms should be advised to use in vitro fertilization with intracytoplasmic sperm injection instead of IUI. Expand
The impact of endometrioma and laparoscopic cystectomy on serum anti-Müllerian hormone levels
TLDR
Bilateral endometrioma exerts a more profound negative impact on ovarian reserve than unilateral endometRIoma, regardless of either conservative or surgical intervention. Expand
Dual trigger with combination of gonadotropin-releasing hormone agonist and human chorionic gonadotropin significantly improves the live-birth rate for normal responders in GnRH-antagonist cycles.
TLDR
Dual trigger of final oocyte maturation with a GnRH-agonist and a standard dosage of hCG in normal responders statistically significantly improves implantation, clinical pregnancy, and live-birth rates in Gn RH-antagonist IVF cycles. Expand
Involvement of the Serine Protease Inhibitor, SERPINE2, and the Urokinase Plasminogen Activator in Cumulus Expansion and Oocyte Maturation
TLDR
SerPINE2 and PLAU are involved in cumulus expansion and oocyte maturation, probably by decreasing cumulus matrix gene expression as well as reducing cumulus hyaluronan contents and inhibiting PLAU activity. Expand
Correlation of cumulus gene expression of GJA1, PRSS35, PTX3, and SERPINE2 with oocyte maturation, fertilization, and embryo development
TLDR
Cumulus GJA1, PRSS35, PTX3, and SERPINE2 may not be considered as marker genes for predicting embryo morphology because of the weak correlation with oocyte maturation, fertilization, and early embryo development. Expand
SPINKL, a Kazal-type serine protease inhibitor-like protein purified from mouse seminal vesicle fluid, is able to inhibit sperm capacitation.
TLDR
The SPINKL protein was able to bind onto sperm and enhance sperm motility and be able to suppress BSA-stimulated sperm capacitation and block sperm-oocyte interactions in vitro, suggesting that SPinkL may be a decapacitation factor. Expand
Cleavage speed and implantation potential of early-cleavage embryos in IVF or ICSI cycles
TLDR
Results indicate that early-cleavage embryos have a higher rate of normal development and develop into better quality embryos on day 3, resulting in more and higher quality embryos to choose from for day-3 embryo transfer. Expand
The predictability of serum anti-Müllerian level in IVF/ICSI outcomes for patients of advanced reproductive age
TLDR
Two criteria: age greater than or equal to 40 years and serum AMH level in the lowest tertile of the matching age group, may be used as markers of futility for counseling IVF/ICSI candidates. Expand
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