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Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain.
Cell death has been reported in the CNS in models of neuropathic pain (Sugimoto et al., 1990; Whiteside and Munglani, 2001; Scholz et al., 2005; Fuccio et al., 2009). In our present study, weExpand
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Spinal 5-HT3 receptors mediate descending facilitation and contribute to behavioral hypersensitivity via a reciprocal neuron-glial signaling cascade
BackgroundIt has been recently recognized that the descending serotonin (5-HT) system from the rostral ventromedial medulla (RVM) in the brainstem and the 5-HT3 receptor subtype in the spinal dorsalExpand
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Limits of arbitrage and idiosyncratic volatility: Evidence from China stock market
This study examines how limits of arbitrage can affect the pricing of idiosyncratic volatility. Using both unique trading constraints in the Chinese stock market and other commonly-usedExpand
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Predicting Axonal Response to Molecular Gradients with a Computational Model of Filopodial Dynamics
Axons are often guided to their targets in the developing nervous system by attractive or repulsive molecular concentration gradients. We propose a computational model for gradient sensing andExpand
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Response of 1 × 2 pile group under eccentric lateral loading
Abstract A large scale model test of a 1 × 2 pile group was conducted in silts to investigate its behavior under eccentric lateral loading. The model pile group consisted of two well instrumentedExpand
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Bone Marrow Stromal Cells Produce Long‐Term Pain Relief in Rat Models of Persistent Pain
Chronic pain conditions are difficult to treat and are major health problems. Bone marrow stromal cells (BMSCs) have generated considerable interest as a candidate for cell‐based therapy. BMSCs areExpand
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Spinal 5-HT3 Receptor Activation Induces Behavioral Hypersensitivity via a Neuronal-Glial-Neuronal Signaling Cascade
Recent studies indicate that the descending serotonin (5-HT) system from the rostral ventromedial medulla (RVM) in the brainstem and the 5-HT3 receptor subtype in the spinal dorsal horn are involvedExpand
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Silymarin Ameliorates Metabolic Dysfunction Associated with Diet-Induced Obesity via Activation of Farnesyl X Receptor
Background and purpose: Silymarin, a standardized extract of the milk thistle seeds, has been widely used to treat chronic hepatitis, cirrhosis, and other types of toxic liver damage. DespiteExpand
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Neuronal Loss in the Rostral Ventromedial Medulla in a Rat Model of Neuropathic Pain
Cell death has been reported in the CNS in models of neuropathic pain (Sugimoto et al., 1990; Whiteside and Munglani, 2001; Scholz et al., 2005; Fuccio et al., 2009). In our present study, weExpand
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A Learning Rule for Local Synaptic Interactions Between Excitation and Shunting Inhibition
The basic requirement for direction selectivity is a nonlinear interaction between two different inputs in space-time. In some models, the interaction is hypothesized to occur between excitation andExpand
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