Ming-Che Ho

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Whether monoamine oxidase inhibitors (MAOIs) can be used to suppress the reinforcing effect of cocaine remains unknown. This study was undertaken to examine effects of a long-term dosing regimen with selective MAOIs on cocaine and food reward. Since single dose of clorgyline (2 mg/kg), deprenyl (1 mg/kg), and pargyline (10 mg/kg) did not acutely affect(More)
Systemic lipopolysaccharide (LPS) treatment may affect methamphetamine (MA)-induced nigrostriatal dopamine (DA) depletion. This study was undertaken to determine the critical time window for the protective effects of LPS treatment and the underlying mechanisms. An LPS injection (1 mg/kg) 72 h before or 2 h after MA treatment [three consecutive, subcutaneous(More)
Drug memory plays an important role in priming subsequent drug use. We used drug-induced conditioned place preference (CPP) as a paradigm to study such drug memory. In this paradigm, repeated association of specific environmental cues with abused drug-induced subjective euphoria has been suggested to motivate later biased approaching behavior toward the(More)
We hereby report that repeated administration of ketamine (350 mg/kg in total) and methamphetamine (30 mg/kg in total) causes specific glutamatergic and dopaminergic neuron deficits, respectively, in adult mouse brain. Acute ketamine did not affect basal body temperature or the later methamphetamine-induced hyperthermia. However, pretreatment with repeated(More)
Currently, joint use of ketamine and 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) represents a specific combination of polydrug abuse. Long-lasting and even aggravated central neuronal toxicity associated with mixing ketamine and MDMA use is of special concern. This study was undertaken to examine the modulating effects of ketamine treatment on later(More)
This paper proposes an effective fusion of neural networks and grey modeling for adaptive electricity load forecasting. The fusion employs the complementary strength of these two appealing techniques. In terms of forecasting accuracy, the proposed fusion scheme outperforms the individual ones and the statistical autoregressive methods according to the(More)
Among the many techniques for tracking moving objects, the particle filter strongly attracts the researchers and developers for its simplicity and effectiveness. Two major problems suffered from the particle filter are the slow tracking speed caused by the examination of a large number of randomly generated particle samples and the position drifting of the(More)
This paper proposes a novel method to detect faces in color images with a wide range of variations in head poses, face tilting, facial expressions and body interferences. The proposed algorithm can locates not only the face regions, but also some important facial components such as month corners and eyes. The experimental results show that the proposed(More)
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