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• Background: The purpose of the investigation was to ascertain the prevalence of dry eye in new outpatients. • Methods: A total of 2127 consecutive new outpatients seen in eight Japanese centers from April 1992 to January 1993 underwent comprehensive examinations, including double vital staining and measurement of tear film break-up time, basal tear(More)
BACKGROUND The motor cortex in the human brain can be modulated by the application of transcranial static magnetic field stimulation (tSMS) through the scalp. However, the effect of tSMS on the excitability of the primary somatosensory cortex (S1) in humans has never been examined. OBJECTIVE This study was performed to investigate the possibility of(More)
BACKGROUND Psychophysiological processing has been reported to play a crucial role in irritable bowel syndrome (IBS) but there has been no report on modulation of the stress marker chromogranin A (CgA) resulting from muscle stretching. We hypothesized that abdominal muscle stretching as a passive operation would have a beneficial effect on a biochemical(More)
The aim of the present study was to investigate the EMG-joint angle relationship during voluntary contraction with maximum effort and the differences in activity among three hamstring muscles during knee flexion. Ten healthy subjects performed maximum voluntary isometric and isokinetic knee flexion. The isometric tests were performed for 5 s at knee angles(More)
OBJECTIVE To investigate the projection of muscle afferents to the sensorimotor cortex after voluntary finger movement by using magnetoencephalography (MEG). METHODS The movement-evoked magnetic fields (MEFs) after voluntary index-finger extension were recorded by a 204-channel whole-head MEG system. Somatosensory-evoked magnetic fields (SEFs) were(More)
OBJECTIVE Magnetoencephalography (MEG) recordings were performed to investigate the cortical activation following tactile-on and tactile-off stimulation. METHODS We used a 306-ch whole-head MEG system and a tactile stimulator driven by a piezoelectric actuator. Tactile stimuli were applied to the tip of right index finger. The interstimulus interval was(More)
We examined the amplitude and latency of movement-related cerebral field (MRCF) waveforms, the generator and afferent feedback of movement-evoked field 1 (MEF1), and the relationship between motor field neuromagnetic activity and electromyographic activity during performance of two types of voluntary index extension. Eight healthy, right-handed male(More)
The posterior parietal cortex (PPC) is strongly related to task performance by evaluating sensory cues and visually guided movements. Sensorimotor processing is improved by task repetition as indicated by reduced response time. We investigated practice-induced changes in PPC visuomotor processing during a Go/NoGo task in humans using 306-channel(More)
OBJECTIVE The purposes of the present study were to investigate the feasibility of using a skin sensor to represent the first and third metacarpal bone, to verify that there was no significant relative motion between the skin of the third metacarpal bone and trapezium bony segment and to measure thumb metacarpal motion with respect to the hand (third(More)
OBJECTIVE This study was performed to elucidate whether transcranial direct current stimulation (tDCS) over the motor association cortex modifies the excitability of primary motor (M1) and somatosensory (S1) cortices via neuronal connectivity. METHODS Anodal, cathodal, and sham tDCS (1 mA) over the left motor association cortex was applied to 10 subjects(More)