Mine Silindir

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Levodopa administration as a gold standard in Parkinson’s disease (PD) treatment is very valuable, however, long-term administration may cause some motor complications such as abnormal unintended movements and shortening response to each dose (wearing off phenomenon). Dopamine agonists were developed to reduce duration of immobile off periods and dependence(More)
Among different imaging modalities, Positron Emission Tomography (PET) gained importance in routine hospital practice depending on ability to diagnose diseases in early stages and tracing of therapy by obtaining metabolic information. The combination of PET with Computed Tomography (CT) forms hybrid imaging modality that gives chance to obtain better images(More)
Sterilization is used in a varity of industry field and a strictly required process for some products used in sterile regions of the body like some medical devices and parenteral drugs. Although there are many kinds of sterilization methods according to physicochemical properties of the substances, the use of radiation in sterilization has many advantages(More)
UNLABELLED The interaction of radiation, whether it has natural or artificial, electromagnetic or particle-type characterizations, with materials causes different effects depending on the dose and type of radiation and physicochemical properties of the material. In the medical field, understanding the effect of radiation on a variety of materials including(More)
Molecular imaging is a relatively new discipline with a crucial role in diagnosis and treatment tracing of diseases through characterization and quantification of biological processes at cellular and sub-cellular levels of living organisms. These molecular targeted systems can be conjugated with contrast agents or radioligands to obtain specific molecular(More)
Radiopharmaceuticals are radioactive compounds that are prepared by a radiopharmasist and used in Nuclear Medicine departments for diagnostic or therapeutic purposes of human diseases. They are generally used i.v. so they have to be sterile and apyrogenic like other parenteral drugs. Effecting in a correct way and localising in the desired tissue with a(More)
Among currently used cancer imaging methods, nuclear medicine modalities provide metabolic information, whereas modalities in radiology provide anatomical information. However, different modalities, having different acquisition times in separate machines, decrease the specificity and accuracy of images. To solve this problem, hybrid imaging modalities were(More)
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