Learn More
Central pain syndrome (CPS) is a debilitating state and one of the consequences of spinal cord injury in patients. Many pathophysiological aspects of CPS are not well documented. Spinal glia activation has been identified as a key factor in the sensory component of chronic pain. In this study, the role of glial subtypes in the process of CPS induced by(More)
Glutathione S-transferases (GSTs) are a superfamily of dimeric proteins catalyzing the conjugation of glutathione with a wide variety of compounds and provide a strong antioxidant function by neutralizing electrophiles and free radicals. The subunits of the GSTs family are placed into several classes including theta (GSTθ). The aim of this study was to(More)
In our previous study we showed that central pain syndrome (CPS) induced by electrolytic injury caused in the unilateral spinothalamic tract (STT) is a concomitant of glial alteration at the site of injury. Here, we investigated the activity of glial cells in thalamic ventral posterolateral nuclei (VPL) and their contribution to CPS. We also examined(More)
  • 1