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INTRODUCTION Adverse drug reactions (ADR) increase morbidity and mortality; potential drug-drug interactions (DDI) increase the probability of ADR. Studies have proven that computerized drug-interaction alert systems (DIAS) might reduce medication errors and potential adverse events. However, the relatively high override rates obscure the benefits of alert(More)
BACKGROUND Hospital-acquired infections (HAI) are associated with increased attributable morbidity, mortality, prolonged hospitalization, and economic costs. A simple, reliable prediction model for HAI has great clinical relevance. The objective of this study is to develop a scoring system to predict HAI that was derived from Logistic Regression (LR) and(More)
INTRODUCTION Maintaining a large diagnostic knowledge base (KB) is a demanding task for any person or organization. Future clinical decision support system (CDSS) may rely on multiple, smaller and more focused KBs developed and maintained at different locations that work together seamlessly. A cross-domain inference tool has great clinical import and(More)
OBJECTIVES To surveyed the quantities, types, and related information of potential drug-drug interactions (DDIs) and estimate the off-label use percentage of pediatric outpatient prescriptions for newborns and infants from the National Health Insurance Research Database (NHIRD) of Taiwan. BACKGROUND Adverse drug reactions (ADR) may cause morbidity and(More)
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