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The advent of multicores presents a promising opportunity for speeding up sequential programs via profile-based speculative parallelization of these programs. In this paper we present a novel solution for efficiently supporting software speculation on multicore processors. We propose the Copy or Discard (CorD) execution model in which the state of(More)
Global, 30-m resolution continuous fields of tree cover: Landsat-based rescaling of MODIS vegetation continuous fields with lidar-based estimates of error Joseph O. Sexton a , Xiao-Peng Song a , Min Feng a , Praveen Noojipady a , Anupam Anand a , Chengquan Huang a , Do-Hyung Kim a , Kathrine M. Collins a , Saurabh Channan a , Charlene DiMiceli b & John R.(More)
The Rb-E2F pathway drives cell cycle progression and cell proliferation, and the molecular strategies safeguarding its activity are not fully understood. Here we report that E2F1 directly transactivates miR-449a/b. miR-449a/b targets and inhibits oncogenic CDK6 and CDC25A, resulting in pRb dephosphorylation and cell cycle arrest at G1 phase, revealing a(More)
The availability of multicore processors has led to significant interest in compiler techniques for speculative parallelization of sequential programs. Isolation of speculative state from non-speculative state forms the basis of such speculative techniques as this separation enables recovery from misspeculations. In our prior work on CorD [35,36] we showed(More)
"Demonstration of a conceptual model for using LiDAR to improve the estimation of floodwater mitigation potential of Prairie Pothole Region wetlands" (2011). s u m m a r y Recent flood events in the Prairie Pothole Region of North America have stimulated interest in modeling water storage capacities of wetlands and their surrounding catchments to facilitate(More)
In this paper we present an approach to parallel programming called SpiceC. SpiceC simplifies the task of parallel programming through a combination of an intuitive computation model and SpiceC directives. The SpiceC parallel computation model consists of multiple threads where every thread has a private space for data and all threads share data via a(More)
Structural maintenance of chromosomes (SMC) proteins play fundamental roles in many aspects of chromosome organization and dynamics. The SMC complexes form unique structures with long coiled-coil arms folded at a hinge domain, so that the globular N- and C-terminal domains are brought together to form a "head." Within the Smc5-Smc6 complex, we previously(More)
The water index (WI) is designed to highlight inland water bodies in remotely sensed imagery. The application of WI for water body mapping is mainly based on the thresholding method. However, there are three primary difficulties with this method: (1) inefficient identification of mixed water pixels; (2) confusion of water bodies with background noise; and(More)
OBJECTIVE To assess methodological quality of clinical studies using Aidi Injection as an adjunct therapy for non-small cell lung cancer (NSCLC) and to evaluate the effects of Aidi Injection. METHODS PubMed (1980-2008), Cochrane Central Register of Controlled Trials (The Cochrane Library, Issue 3, 2008), EMBASE (1984-2008), CancerLit (1996-2003), CBMdisc(More)