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CONTEXT Patients with unstable angina/non-ST-segment elevation myocardial infarction (MI) (UA/NSTEMI) present with a wide spectrum of risk for death and cardiac ischemic events. OBJECTIVE To develop a simple risk score that has broad applicability, is easily calculated at patient presentation, does not require a computer, and identifies patients with(More)
BACKGROUND Antithrombotic therapy with heparin plus aspirin reduces the rate of ischemic events in patients with unstable coronary artery disease. Low-molecular-weight heparin has a more predictable anticoagulant effect than standard unfractionated heparin, is easier to administer, and does not require monitoring. METHODS In a double-blind,(More)
The development of a widened mediastinum in patients with neoplastic disease frequently indicates tumor recurrence or spread. Seven cases of mediastinal widening in children with a variety of neoplasms are described wherein the etiology is either proven or strongly suspected to be benign thymic enlargement. Awareness of this benign etiology for mediastinal(More)
BACKGROUND Two phase III trials of enoxaparin for unstable angina/non-Q-wave myocardial infarction have shown it to be superior to unfractionated heparin for preventing a composite of death and cardiac ischemic events. A prospectively planned meta-analysis was performed to provide a more precise estimate of the effects of enoxaparin on multiple end points.(More)
OVER THE LAST few years clinical/pathologic observations and experimental investigation have led us to a better understanding of the pathogenetic factors leading to the acute coronary syndromes: unstable angina , myocardial infarction, and ischemic sudden death. The elegant pathologic studies of Falk' and Da-vies and Thomas2 have emphasized that thrombus(More)
The present studies demonstrate that daily worry level is predictive of cognitive processing differences and that these differences are an effect of negative thoughts. In Study 1, worriers (those who reported 50% or greater daily worry) and non-worriers performed a categorization task. The groups did not differ when the stimulus was a clear member or(More)
The presentation, cardiac anatomy and utility of programmed ventricular stimulation in seven patients with sustained ventricular tachycardia associated with sarcoidosis are described. The mean patient age was 38 +/- 8 years. Pulmonary involvement was apparent in three patients and no systemic manifestations of sarcoidosis were present in one patient. All(More)
Transluminal coronary angioplasty can serve as a model for controlled coronary artery occlusion and reperfusion which enables assessment of short-term changes in collateral vessel filling in patients with severe atherosclerotic coronary artery disease. In 16 patients with isolated left anterior descending or right coronary artery disease (greater than or(More)
OBJECTIVES This study presents clinical data from the first large registry of aortic counterpulsation, a computerized database that incorporates prospectively gathered data on indications for intra-aortic balloon counterpulsation (IABP) use, patient demographics, concomitant medication and in-hospital outcomes and complications. BACKGROUND The(More)
BACKGROUND The purpose of this study was to compare combination antithrombotic therapy with aspirin plus anticoagulation versus aspirin alone, when added to conventional antianginal therapy in patients with unstable rest angina or non-Q-wave myocardial infarction who were nonprior aspirin users. METHODS AND RESULTS Two hundred fourteen patients were(More)