Miloslav Špaček

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Limited insights into the pathophysiology of the atherosclerotic carotid stenosis are available in vivo. We conducted a prospective study to assess safety and feasibility of intravascular ultrasound (IVUS) combined with near-infrared spectroscopy (NIRS) in carotid arteries. In addition, we described the size and the distribution of lipid rich plaques in(More)
OBJECTIVES To report on early and mid-term outcomes of carotid artery stenting (CAS) in patients with angiographic string sign (SS). BACKGROUND Little is known about the prognosis of patients with carotid SS treated by CAS. METHODS We retrospectively evaluated early and mid-term outcomes, together with ultrasound findings, in patients with SS treated by(More)
In chronic lymphocytic leukemia (CLL) the level of minimal residual disease (MRD) after therapy is an independent predictor of outcome. Given the increasing number of new agents being explored for CLL therapy, using MRD as a surrogate could greatly reduce the time necessary to assess their efficacy. In this European Research Initiative on CLL (ERIC) project(More)
BACKGROUND Carotid artery stenting (CAS) is the method of choice for carotid artery revascularization of patients at high risk for carotid endarterectomy. In this study, we compared the midterm results of CAS in patients with unilateral versus bilateral carotid artery disease. METHODS AND RESULTS This is a retrospective analysis of 1-year outcome of 273(More)
INTRODUCTION Little is known about the prognosis of moderate versus critical carotid stenosis treated by carotid artery stenting (CAS). MATERIAL AND METHODS This was a retrospective analysis of a single-centre registry including 271 consecutive patients (69 ±9 years, 87% at high risk for surgery), in whom 308 procedures were performed. The study included(More)
Bovine aortic arch refers to the most common variant of aortic arch branching in humans. This configuration can be found in approximately 27% of the population and can be further divided into 2 subtypes. In the less usual subtype (7%, Figure 1 – panel A), the innominate artery (usually 1-2.5 cm long) trifurcates into the left common carotid artery, the(More)
Surgical carotid endarterectomy (CEA) was long considered the standard approach for the treatment of atherosclerotic carotid artery disease. This was based on results of several randomized trials demonstrating its effectiveness over the best medical therapy. In the past two decades, patients identified high-risk for surgery were offered carotid artery(More)
INTRODUCTION The aim of this study is to report the feasibility, safety, and 1-year restenosis rate of carotid artery stenting (CAS) without post-dilation. METHODS Between April 2006 and November 2009, 254 consecutive patients (68.7 ± 8.5 years old, 31% symptomatic) underwent 308 CAS procedures with the intention of avoiding post-dilation (eligibility(More)
Takayasu arteritis (TA) is an inflammatory disease affecting large and medium-sized arteries and causing occlusive, aneurysmal, or stenotic lesions. It is also known that with chronic course, the disease has a tendency to recur at either the same site or different. We report a patient with TA whose carotid stenosis was initially treated with bare metal(More)