Milen I Georgiev

Publications127
h-index29
Citations2,747
Highly Influential Citations121
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Hairy root type plant in vitro systems as sources of bioactive substances
Abstract“Hairy root” systems, obtained by transforming plant tissues with the “natural genetic engineer” Agrobacterium rhizogenes, have been known for more than three decades. To date, hairy root… Expand
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Verbascoside--a review of its occurrence, (bio)synthesis and pharmacological significance.
Phenylethanoid glycosides are naturally occurring water-soluble compounds with remarkable biological properties that are widely distributed in the plant kingdom. Verbascoside is a phenylethanoid… Expand
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Optimization of Rosmarinic Acid Production by Lavandula vera MM Plant Cell Suspension in a Laboratory Bioreactor
The all‐round effect of dissolved oxygen concentration, agitation speed, and temperature on the rosmarinic acid production by Lavandula veraMM cell suspension was studied in a 3‐L laboratory… Expand
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Advances in the biotechnological glycosylation of valuable flavonoids.
The natural flavonoids, especially their glycosides, are the most abundant polyphenols in foods and have diverse bioactivities. The biotransformation of flavonoid aglycones into their glycosides is… Expand
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Genetically transformed roots: from plant disease to biotechnological resource.
Hairy root syndrome is a disease that is induced by Agrobacterium rhizogenes infection and characterized by a proliferation of excessively branching roots. However, in the past 30 years A.… Expand
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Elicitation of rosmarinic acid by Lavandula vera MM cell suspension culture with abiotic elicitors
The growth of Lavandula vera MM plant cell suspension culture and rosmarinic acid biosynthesis under elicitation with benzothiadiazole and methyl jasmonate were investigated. Upon elicitation with 50… Expand
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Hosting the plant cells in vitro: recent trends in bioreactors
Biotechnological production of high-value metabolites and therapeutic proteins by plant in vitro systems has been considered as an attractive alternative of classical technologies. Numerous… Expand
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Galanthamine production by Leucojum aestivum in vitro systems
Abstract The callus induction from young fruits of Leucojum aestivum was performed on Murashige–Skoog nutrient medium supplemented with 4 mg/L 2,4 dichlorphenoxyacetic and 2 mg/L 6-benzylamynopurine.… Expand
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Enhanced Rosmarinic Acid Production by Lavandula vera MM Cell Suspension Culture through Elicitation with Vanadyl Sulfate
The influence of elicitation on rosmarinic acid biosynthesis by Lavandula vera MM cell suspension culture was investigated using vanadyl sulfate as an abiotic elicitor. It was established that 12 h… Expand
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Oxidative stress and chronic inflammation in osteoarthritis: can NRF2 counteract these partners in crime?
Osteoarthritis (OA) is an age‐related joint degenerative disease associated with pain, joint deformity, and disability. The disease starts with cartilage damage but then progressively involves… Expand
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