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BACKGROUND A circalunar cycle is thought to be female sex specific. Results of studies observing the relationship of testosterone and spatial abilities are controversial. OBJECTIVE To describe the infradian variations of testosterone and the correlations between salivary testosterone levels and spatial abilities in young healthy volunteers of both sexes.(More)
UNLABELLED The aim of the study was the analysis of the new molecular genetic immunomarkers (p53, c-erbB-2, Ki 67, bcl-2) hormonal receptors (ER, PR) and ploidy disturbances and their relation to the most important prognostic factors for endometrial cancer. The study group consisted of 135 endometrial cancer patients. Biopsies of the tumours obtained at(More)
OBJECTIVE To summarise which metalloproteinases and specific inhibitors have been already described, their regulatory mechanisms, the connection with implantation and in cases of tumour invasion. In conclusion we would like to point to the possibilities of practical use of this information. DESIGN A literature review. SETTING Department of Obstetrics(More)
OBJECTIVE The aim of this study was to evaluate the feasibility of pre-operative lymphoscintigraphy and radio-guided surgery in endometrial cancer patients after intramyometrial administration of labelled colloid. DESIGN Prospective study. SETTING Department of Obstetrics and Gynaecology of the Palacký University Medical School and University Hospital,(More)
AIM To study inflammatory response and nutritional biomarkers in operated endometrial cancer (EC) patients. MATERIALS AND METHODS A total 109 consecutive EC patients undergoing open laparotomy (LT), laparoscopic (LS) or robot-assisted surgery (RS) were studied. Twenty four patients served as controls. Pre- and postoperative levels of inflammatory and(More)
OBJECTIVE The aim of the study was to detect the incidence of thrombophilia FV Leiden, prothrombin G20210A, MTHFR C677T, resistance to activated protein C, and deficiency of protein C and S in pregnant or puerperal women with preeclampsia and control group. DESIGN Case-control study. SETTING Department of Obstetrics and Gynecology, Department of(More)
OBJECTIVE The objectives of this study were to assess the immunohistochemical expression of p53, bcl-2, c-erbB-2, Ki-67, estrogen (ER) and progesterone (PR) receptors, matrix metalloproteinase-7 and -26 (MMP-7 and MMP-26) in endometrial cancer patients and to assess the relation between steroid receptor positivity and other markers. DESIGN Experimental(More)
OBJECTIVE The aim of the study was to detect the incidence of resistance to activated protein C in pregnant or puerperal women with confirmed diagnosis of deep venous thrombosis or pulmonary embolism. DESIGN Case-control study. SETTING Dept. of Obstetrics and Gynaecology, Dept. of Haemato-oncology, Medical Faculty, Palacky University, Olomouc. METHODS(More)
OBJECTIVE There is a growing view that inherited or acquired thrombophilia may predispose a woman towards an adverse pregnancy outcome. The aim of this study was to investigate whether risk factors for placental abruption because of such thrombophilias (such as carriership of factor V Leiden (FVL), prothrombin G20210A gene mutation and homozygous MTHFR(More)
OBJECTIVES The objective of this prospective study was to evaluate fetal fibronectin bedside test (Mast Diagnostica) to rule out preterm labor. STUDY DESIGN 46 patients from between 25 and 36 weeks were included in the study over a six months period. All patients underwent only one cervical sampling at the beginning of the study. The association between(More)