Milan Kolar

Magdalena Chroma2
Aneta Novotna1
Helena Tlaskalova-Hogenova1
Eva Anzenbacherova1
Patrik Mlynarcik1
2Magdalena Chroma
1Aneta Novotna
1Helena Tlaskalova-Hogenova
1Eva Anzenbacherova
1Patrik Mlynarcik
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BACKGROUND Enterobacteriaceae producing ESBL and AmpC enzymes can be associated with failure of antibiotic therapy and related morbidity and mortality. Their routine detection in microbiology laboratories is still a problem. The aim of this study was to compare the sensitivity of selected phenotypic methods. MATERIAL/METHODS A total of 106 strains of the(More)
BACKGROUND During the last decade, the prevalence of carbapenem-resistant Enterobacteriaceae in human patients has increased. Carbapenemase-producing bacteria are usually multidrug resistant. Therefore, early recognition of carbapenemase producers is critical to prevent their spread. OBJECTIVES The objective of this study was to develop the primers for(More)
Azole antifungal ketoconazole (KET) was demonstrated to activate aryl hydrocarbon receptor (AhR). Since clinically used KET is a racemic mixture of two cis-enantiomers (2R,4S)-(+)-KET and (2S,4R)-(-)-KET, we examined the effects of KET enantiomers on AhR signaling pathway. (+)-KET dose-dependently activated AhR in human gene reporter cell line AZ-AHR, and(More)
  • Zuzana Matuskova, Eva Anzenbacherova, Rostislav Vecera, Helena Tlaskalova-Hogenova, Milan Kolar, Pavel Anzenbacher
  • 2014
The growing interest in the composition and effects of microbiota raised the question how drug pharmacokinetics could be influenced by concomitant application of probiotics. The aim of this study was to find whether probiotic E. coli strain Nissle 1917 (EcN) influences the pharmacokinetics of concomitantly taken antiarrhythmic drug amiodarone (AMI). Live(More)
BACKGROUND Acinetobacter baumannii is an opportunistic pathogen posing an increased risk to hospitalized persons, causing nosocomial pneumonias, urinary tract infections and postoperative infections. METHODS Between 1 December 2011 and 30 September 2012, strains of Acinetobacter spp. were isolated from clinical samples obtained from hospitalized patients.(More)
AIM Vacuum-assisted closure (VAC) was primarily designed for the treatment of pressure ulcers or chronic, debilitating wounds. Recently, VAC has become an encouraging treatment modality for sternal wound infection after cardiac surgery, providing superior results to conventional treatment strategies. METHODS From November 2004 to September 2006, 34(More)
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