Milagros Mezcúa

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Pharmaceutical residues in the environment, and their potential toxic effects, have been recognized as one of the emerging research area in the environmental chemistry. The increasing attention, on pharmaceutical residues as potential pollutants, is due that they often have similar physico-chemical behaviour than other harmful xenobiotics which are(More)
This work presents a new multi-residue analytical method based on solid phase extraction (SPE) with Oasis HLB sorbent, followed by gas chromatography tandem mass spectrometry (GC-MS/MS) for the simultaneous determination of a group of 10 acidic and neutral pharmaceuticals and related compounds in wastewaters. The typical derivation step was avoided,(More)
In this study we have developed and evaluated an analytical method for a rapid automated screening and confirmation of a large number of organic micro-contaminants (almost 400) and also the quantification of the positive findings in water samples of different types (surface and wastewaters) using liquid chromatography-electrospray quadrupole-time-of-flight(More)
Liquid chromatography coupled with time-of-flight mass spectrometry (LC/TOFMS) was applied for the identification of four new photodegradation products of triclosan, a major antimicrobial agent used in personal care products. Wastewater samples, spiked at 7 microg/mL with triclosan, were irradiated with natural sunlight in order to generate the(More)
Two GC-MS methods, based on the application of N,O-bis(trimethylsilyl)trifluoroacetamide-derivatization-GC-MS (selected-ion monitoring) and GC-MS-MS without derivatization, respectively, were optimised and applied to the determination of a group of five selected endocrine disrupting compounds (EDCs) in wastewaters. Both methods included solid-phase(More)
The ozonation of an effluent from the secondary clarifier of two Municipal Wastewater Treatment Plants was performed by using alkaline ozone and a combination of ozone and hydrogen peroxide. Alkaline ozonation achieved only a moderate degree of mineralization, essentially concentrated during the first few minutes; but the addition of hydrogen peroxide(More)
In this work, a new multi-residue methodology using liquid chromatography-time-of-flight mass spectrometry (LC-TOF-MS) for the quantitative (routine) analysis of 15 pesticide residues has been developed. The analytical performance of the method was evaluated for different types of fruit and vegetables: pepper, broccoli, tomato, orange, lemon, apple and(More)
The photochemical behaviour of three relevant metabolites of the analgesic and antipyretic drug dipyrone, 4-methylaminoantipyrine (4-MAA), 4-formylaminoantipyrine (4-FAA) and 4-acetylaminoantipyrine (4-AAA), was evaluated under simulated solar irradiation (Suntest system). For 4-MAA, different aqueous solutions (synthetic seawater, freshwater and Milli-Q(More)
Ultra performance liquid chromatography coupled to triple quadrupole tandem mass spectrometry (UPLC-MS/MS) has been applied for the accurate and rapid analysis of nine trace level priority pesticides in water. The UPLC technology, based on the use of columns packed with 1.7 microm porous particles combined with higher pressures than those conventionally(More)
This work reports a rapid and reliable method for the determination of 33 multi-class pesticides in fruit-based soft drinks. The proposed method consists of a sample treatment step based on solid-phase extraction using hydrophilic-lipophilic balanced polymer-based reverse-phase SPE cartridges, followed by identification and quantitation of the target(More)