Miklós Lukács

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OBJECTIVE Previous studies have revealed a loss of functioning motor units in stroke patients. However, it remained unclear whether the motor units are affected randomly or in some specific pattern. We assessed whether there is a selective loss of the large (high recruitment threshold) or the small (low recruitment threshold) motor units following a stroke.(More)
OBJECTIVE To study changes in motor units on the hemiparetic side, and the relationship between these changes and time after stroke onset and hemiparetic severity. METHODS Neurography and concentric needle EMG were performed, and hemiparetic side mean and extreme parameter values were compared with the unaffected side mean and extreme parameter values(More)
Migraine is a painful disorder with a huge impact on individual and public health. We hypothesize that migraine pain originates from a central mechanism that results secondarily in hypersensitivity in peripheral afferents associated with the cerebral and cranial blood vessels. It has previously been shown that application of inflammatory or algesic(More)
OBJECTIVES Previous studies have revealed a selective functional loss of the large, high-threshold motor units in the paretic muscles after lesion of the upper motor neuron. We set out to study the degree and the time course of the reorganization of the motor units following a stroke. METHODS Examinations were performed on 59 patients with a unilateral(More)
Neurogenic inflammation has for decades been considered an important part of migraine pathophysiology. In the present study, we asked the question if administration of a novel kynurenic acid analogue (SZR72), precursor of an excitotoxin antagonist and anti-inflammatory substance, can modify the neurogenic inflammatory response in the trigeminal ganglion.(More)
OBJECTIVE To study mechanisms that are involved in the hyperexcitability of spinal motor neurons in upper motor neuron lesion, by means of F-wave measurements. METHODS F waves from 44 hospitalized stroke patients and 35 healthy controls were recorded from abductor pollicis brevis muscles in the course of two experiments: (1) single stimuli following(More)
Motor units (MUs) are recruited according to the size principle. At low force output, macro-motor unit potentials (macro-MUPs) with small amplitude and area are recorded; MUs with large electrical size fire at high force output. Our objective was to elucidate whether this difference is caused by a higher fiber density (FD) of the MUs recruited at high force(More)
INTRODUCTION The aim of the study was the electrophysiological investigation of thallium induced polyneuropathy. Beyond the rarity of the illness, the motivation of this work was the possibility of following up the pattern of neuronal damage. Thallium is one of the most toxic heavy metal and its wide use increases the chance of chronic or accidental acute(More)