Miki Asano

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Recent studies have suggested that long-term oxytocin administration can alleviate the symptoms of autism spectrum disorder (ASD); however, factors influencing its efficacy are still unclear. We conducted a single-center phase 2, pilot, randomized, double-blind, placebo-controlled, parallel-group, clinical trial in young adults with high-functioning ASD, to(More)
The release of gamma-aminobutyric acid (GABA) from the robust nucleus of the archistriatum (RA) of the zebra finch was examined in slice preparations. Potassium-induced depolarization caused calcium-dependent release of GABA. GABA release by veratrine was blocked by tetrodotoxin. Electrical stimulation of fibers dorsal to RA also released GABA. There was no(More)
BACKGROUND Lower tube voltage has advantages for CT angiography, such as improved contrast OBJECTIVE To evaluate the image quality of low-voltage (70 kV) CT for congenital heart disease and the ability of sinogram-affirmed iterative reconstruction to improve image quality. MATERIALS AND METHODS Forty-six children with congenital heart disease (median(More)
Recent accumulation of sequence and structural data, in conjunction with systematical classification into a set of families, has significantly advanced our understanding of diverse and specific protein functions. Analysis and interpretation of protein family data requires comprehensive sequence and structural alignments. Here, we present a simple scheme for(More)
BACKGROUND Various carotid reconstructions have been used in Takayasu's arteritis (TA) to relieve brain ischemic insult. The indications and guidelines for surgical management, however, have remained poorly defined. The authors present a new reconstructive procedure using the sequential internal thoracic artery (ITA) as the donor for bypass surgery to(More)
This simple, rapid liquid-chromatographic assay of urinary polyamines (putrescine, spermidine, spermine, and cadaverine) involves electrochemical detection with a post-column immobilized enzyme, polyamine oxidase (EC 1.4.3.6) from soybean seedlings. Polyamines are separated by isocratic ion-pairing reversed-phase chromatography, then enzymatically(More)
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