Mikel Esnaola

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Exposure to green space has been associated with better physical and mental health. Although this exposure could also influence cognitive development in children, available epidemiological evidence on such an impact is scarce. This study aimed to assess the association between exposure to green space and measures of cognitive development in primary(More)
Computerized neuropsychological tests offered several advantages for large epidemiological studies to assess child neuropsychological development. We aimed to evaluate the psychometric properties and criterion validity of 2 computerized tests (n-back and attentional network task [ANT]) used to assess the working memory and attention function, respectively.(More)
High-throughput RNA sequencing (RNA-seq) offers unprecedented power to capture the real dynamics of gene expression. Experimental designs with extensive biological replication present a unique opportunity to exploit this feature and distinguish expression profiles with higher resolution. RNA-seq data analysis methods so far have been mostly applied to data(More)
BACKGROUND Air pollution is a suspected developmental neurotoxicant. Many schools are located in close proximity to busy roads, and traffic air pollution peaks when children are at school. We aimed to assess whether exposure of children in primary school to traffic-related air pollutants is associated with impaired cognitive development. METHODS AND(More)
BACKGROUND The available evidence of the effects of air pollution and noise on behavioral development is limited, and it overlooks exposure at schools, where children spend a considerable amount of time. OBJECTIVE We aimed to investigate the associations of exposure to traffic-related air pollutants (TRAPs) and noise at school on behavioral development of(More)
BACKGROUND A few studies have reported associations between traffic-related air pollution exposure at schools and cognitive development. The role of PM components or sources other than traffic on cognitive development has been little explored. OBJECTIVES We aimed to explore the role of PM sources in school air on cognitive development. METHODS A cohort(More)
BACKGROUND Neuropsychological instruments to assess cognitive trajectories during childhood in epidemiological studies are needed. This would improve neurodevelopment characterization in order to identify its potential determinants. We aimed to study whether repeated measures of n-back, a working memory task, detect developmental trajectories in(More)
1 Getting started This document gives an overview of the R package tweeDEseq, which provides statistical procedures for testing differential expression in RNA-seq count data. In fact, these procedures could be applied, in principle, to any kind of count data, other than RNA-seq. The tweeDEseq package offers a function for normalizing count data which(More)
PURPOSE The evidence regarding the role of physical activity (PA) habits on cognitive development in children is still scarce. Our study aimed to assess the association between PA habits and cognitive growth patterns, including working memory (WM) and inattentiveness in a large sample of primary schoolchildren. METHOD This study included 2,897 children(More)
At city level, personal monitoring is the best way to assess people's exposure. However, it is usually estimated from a few monitoring stations. Our aim was to determine the exposure to black carbon (BC) and BC dose for 45 schoolchildren with portable microaethalometers and to evaluate the relationship between personal monitoring and fixed stations at(More)
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