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Stimulation of phospholipase Cbeta by receptor agonists and G proteins has been characterized in crude cerebral membrane preparations, but little is known about their presynaptic localizations and(More)
We have investigated the effect of treatments with the muscarinic acetylcholine receptor agonist, pilocarpine, on the sensitivity of central alpha2-adrenoceptors that regulate the firing activity of(More)
The phosphoinositide signal transduction system, and particularly, phospholipase Cβ isozymes, are relevant in the etiopathogeny of human neuropsychiatric pathologies such as depression. Stimulation(More)
Inositol 1,4,5-trisphosphate (InsP(3)) production in single cerebellar granule neurons (CGNs) grown in culture was measured using the PH domain of phospholipase C delta1 tagged with enhanced green(More)
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